New Trends in Uric Acid Electroanalysis

Author:

Chelmea Ligia123,Badea Mihaela12ORCID,Scarneciu Ioan4,Moga Marius Alexandru4,Dima Lorena12ORCID,Restani Patrizia5ORCID,Murdaca Cecilia5,Ciurescu Daniel4,Gaman Laura Elena6

Affiliation:

1. Department of Fundamental, Prophylactic and Clinical Disciplines, Faculty of Medicine, Transilvania University of Brasov, 500019 Brasov, Romania

2. Research Center for Fundamental Research and Prevention Strategies in Medicine, Research and Development Institute of the Transilvania University of Brasov, 500484 Brasov, Romania

3. Department of Infectious Diseases, Pulmonology and Infectious Diseases Clinical Hospital of Brasov, 500174 Brasov, Romania

4. Department of Medical and Surgical Specialties, Faculty of Medicine, Transilvania University of Brasov, 500019 Brasov, Romania

5. Faculty of Pharmacy, Universita degli Studi di Milano, 20133 Milan, Italy

6. Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania

Abstract

Considering the increasing incidence of hyperuricemia and oxidative stress-related diseases, quantification of uric acid has become essential. Therefore, the evolution on sensing devices being favorable, these questions are more often addressed to the field of medical researchers. As for many metabolites, (bio)sensors provide a reliable method for screening and evaluation of uric acid status. Due to the numerous categories of (bio)sensors available, choosing the appropriate one is a challenge. This study reviews the scientific information concerning the most suitable (bio)sensors for quantification of uric acid, presenting a list of sensors from the last decade, categorized by configurations and materials. In addition, this review includes a comparison of sensors according to their interference behavior and sensitivity, offering an objective perspective for identifying devices that are suitable for clinical applications.

Publisher

MDPI AG

Subject

Physical and Theoretical Chemistry,Analytical Chemistry

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