Theoretical and Numerical Simulations on the Hepatitis B Virus Model through a Piecewise Fractional Order

Author:

Aldwoah K. A.1,Almalahi Mohammed A.2ORCID,Shah Kamal34

Affiliation:

1. Department of Mathematics, Faculty of Science, Islamic University of Madinah, Al Madinah 42351, Saudi Arabia

2. Department of Mathematics, Hajjah University, Hajjah 00967, Yemen

3. Department of Mathematics, University of Malakand, Chakdara Dir(L) 18000, Khyber Pakhtunkhawa, Pakistan

4. Department of Computer Science and Mathematics, Lebanese American University, Byblos P.O. Box 36, Lebanon

Abstract

In this study, we introduce the dynamics of a Hepatitis B virus (HBV) model with the class of asymptomatic carriers and conduct a comprehensive analysis to explore its theoretical aspects and examine the crossover effect within the HBV model. To investigate the crossover behavior of the operators, we divide the study interval into two subintervals. In the first interval, the classical derivative is employed to study the qualitative properties of the proposed system, while in the second interval, we utilize the ABC fractional differential operator. Consequently, the study is initiated using the piecewise Atangana–Baleanu derivative framework for the systems. The HBV model is then analyzed to determine the existence, Hyers–Ulam (HU) stability, and disease-free equilibrium point of the model. Moreover, we showcase the application of an Adams-type predictor-corrector (PC) technique for Atangana–Baleanu derivatives and an extended Adams–Bashforth–Moulton (ABM) method for Caputo derivatives through numerical results. Subsequently, we employ computational methods to numerically solve the models and visually present the obtained outcomes using different fractional-order values. This network is designed to provide more precise information for disease modeling, considering that communities often interact with one another, and the rate of disease spread is influenced by this factor.

Publisher

MDPI AG

Subject

Statistics and Probability,Statistical and Nonlinear Physics,Analysis

Reference30 articles.

1. (2018, February 12). World Health Organization (WHO) Media Centre. Available online: http://www.who.int/mediacentre/factsheets/fs204/en/.

2. Hepatitis B in a high prevalence New Zealand population: A mathematical model applied to infection control policy;Thornley;J. Theor. Biol.,2008

3. Modelling the epidemiology of hepatitis B in New Zealand;Mann;J. Theoret. Biol.,2011

4. Modelling diseases with relapse and nonlinear incidence of infection: A multi-group epidemic model;Wang;J. Biolog. Dyn.,2014

5. A mathematical model of hepatitis B virus transmission and its application for vaccination strategy in China;Zhao;Int. J. Epidemiol.,2000

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