Abstract
Aflatoxin B1 (AFB1) is a mycotoxin known to impair human and animal health. It is also believed to have a deleterious effect on ruminal nutrient digestibility under in vitro batch culture systems. The objective of this study was to evaluate the effects of increasing the dose of AFB1 on ruminal dry matter and nutrient digestibility, fermentation profile, and N flows using a dual-flow continuous culture system fed a diet formulated for lactating dairy cows. Eight fermenter vessels were used in a replicated 4 × 4 Latin square design with 10 d periods (7 d adaptation and 3 d sample collection). Treatments were randomly applied to fermenters on diet DM basis: (1) 0 μg of AFB1/kg of DM (Control); (2) 50 μg of AFB1/kg of DM (AF50); (3) 100 μg of AFB1/kg of DM (AF100); and (4) 150 μg of AFB1/kg of DM (AF150). Treatments did not affect nutrient digestibility, fermentation, and N flows. Aflatoxin B1 concentration in ruminal fluid increased with dose but decreased to undetectable levels after 4 h post-dosing. In conclusion, adding incremental doses of AFB1 did not affect ruminal fermentation, digestibility of nutrients, and N flows in a dual-flow continuous culture system fed diets formulated for lactating dairy cows.
Subject
Health, Toxicology and Mutagenesis,Toxicology
Reference41 articles.
1. Epidemiology of Aflatoxin Formation by Aspergillus Flavus;Diener;Ann. Rev. Phytopathol.,1987
2. Toxic Metabolites of Aspergillus Flavus;Hartley;Nature,1963
3. Groundnut toxicity: An examination for toxin in human food products from animals fed toxic groundnut meal;Allcroft;Vet. Rec.,1963
4. Toxicological and Medical Aspects of Aspergillus-Derived Mycotoxins Entering the Feed and Food Chain;Madar;Front. Microbiol.,2020
5. Peles, F., Sipos, P., Kovács, S., Gyori, Z., Pócsi, I., and Pusztahelyi, T. (2021). Biological Control and Mitigation of Aflatoxin Contamination in Commodities. Toxins., 13.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献