The Feasibility of Semi-Continuous and Multi-Frequency Thoracic Bioimpedance Measurements by a Wearable Device during Fluid Changes in Hemodialysis Patients-Reference-Cited by-同舟云学术

The Feasibility of Semi-Continuous and Multi-Frequency Thoracic Bioimpedance Measurements by a Wearable Device during Fluid Changes in Hemodialysis Patients

Published:2024-03-15 Issue:6 Volume:24 Page:1890
ISSN:1424-8220
Container-title:Sensors
language:en
Short-container-title:Sensors

Author:

Schoutteten Melanie K.¹²³^ORCID,Lindeboom Lucas³,De Cannière Hélène¹²^ORCID,Pieters Zoë⁴^ORCID,Bruckers Liesbeth⁴^ORCID,Brys Astrid D. H.⁵,van der Heijden Patrick³,De Moor Bart¹⁶,Peeters Jacques⁷,Van Hoof Chris⁸⁹,Groenendaal Willemijn³,Kooman Jeroen P.¹⁰¹¹,Vandervoort Pieter M.¹²³¹²

Affiliation:

1. Limburg Clinical Research Center/Mobile Health Unit, Faculty of Biomedical and Life Sciences, Hasselt University, Agoralaan, 3590 Diepenbeek, Belgium

2. Ziekenhuis Oost Limburg, Department of Future Health, Ziekenhuis Oost Limburg Genk, Synaps Park 1, 3600 Genk, Belgium

3. Department of Health Research, imec the Netherlands/Holst Centre, High Tech Campus 31, 5656 AE Eindhoven, The Netherlands

4. Data Science Institute, Hasselt University, 3500 Hasselt, Belgium

5. Division of Geriatrics, Department of Internal Medicine, Maastricht University Medical Centre+, P. Debyelaan 25, 6202 AZ Maastricht, The Netherlands

6. Department of Nephrology, Jessa Ziekenhuis, Stadsomvaart 1, 3500 Hasselt, Belgium

7. Department of Nephrology, Ziekenhuis Oost Limburg, Synaps Park 1, 3600 Genk, Belgium

8. Imec Belgium, Kapeldreef 75, 3001 Leuven, Belgium

9. Department of Electrical Engineering (ESAT), Katholieke Universiteit Leuven, Kasteelpark Arenberg 10, 3001 Leuven, Belgium

10. Division of Nephrology, Department of Internal Medicine, Maastricht University Medical Centre+, P. Debyelaan 25, 6202 AZ Maastricht, The Netherlands

11. NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, The Netherlands

12. Department of Cardiology, Ziekenhuis Oost Limburg, Synaps Park 1, 3600 Genk, Belgium

Abstract

Repeated single-point measurements of thoracic bioimpedance at a single (low) frequency are strongly related to fluid changes during hemodialysis. Extension to semi-continuous measurements may provide longitudinal details in the time pattern of the bioimpedance signal, and multi-frequency measurements may add in-depth information on the distribution between intra- and extracellular fluid. This study aimed to investigate the feasibility of semi-continuous multi-frequency thoracic bioimpedance measurements by a wearable device in hemodialysis patients. Therefore, thoracic bioimpedance was recorded semi-continuously (i.e., every ten minutes) at nine frequencies (8–160 kHz) in 68 patients during two consecutive hemodialysis sessions, complemented by a single-point measurement at home in-between both sessions. On average, the resistance signals increased during both hemodialysis sessions and decreased during the interdialytic interval. The increase during dialysis was larger at 8 kHz (∆ 32.6 Ω during session 1 and ∆ 10 Ω during session 2), compared to 160 kHz (∆ 29.5 Ω during session 1 and ∆ 5.1 Ω during session 2). Whereas the resistance at 8 kHz showed a linear time pattern, the evolution of the resistance at 160 kHz was significantly different (p < 0.0001). Measuring bioimpedance semi-continuously and with a multi-frequency current is a major step forward in the understanding of fluid dynamics in hemodialysis patients. This study paves the road towards remote fluid monitoring.

Publisher

MDPI AG

Link

https://www.mdpi.com/1424-8220/24/6/1890/pdf

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