1. Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland
2. Shannon Applied Biotechnology Centre, Technological University of the Shannon, Moylish Park, V94 EC5T Limerick, Ireland
3. Department of Chemistry, School of Sciences, International Hellenic University, Saint Luke, GR65404 Kavala, Greece
4. Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA