Breast Cancer Detection with an Ensemble of Deep Learning Networks Using a Consensus-Adaptive Weighting Method

Author:

Dehghan Rouzi Mohammad1ORCID,Moshiri Behzad12ORCID,Khoshnevisan Mohammad3,Akhaee Mohammad Ali1,Jaryani Farhang4ORCID,Salehi Nasab Samaneh5,Lee Myeounggon6ORCID

Affiliation:

1. School of Electrical and computer Engineering, College of Engineering, University of Tehran, Tehran 14174-66191, Iran

2. Department of Electrical and Computer Engineering, University of Waterloo, Ontario, ON N2L 3G1, Canada

3. College of Science, Northeastern University, Boston, MA 02115, USA

4. Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA

5. Department of Computer Engineering, Lorestan University, Khorramabad 68151-44316, Iran

6. College of Health Sciences, Dong-A University, Saha-gu, Busan 49315, Republic of Korea

Abstract

Breast cancer’s high mortality rate is often linked to late diagnosis, with mammograms as key but sometimes limited tools in early detection. To enhance diagnostic accuracy and speed, this study introduces a novel computer-aided detection (CAD) ensemble system. This system incorporates advanced deep learning networks—EfficientNet, Xception, MobileNetV2, InceptionV3, and Resnet50—integrated via our innovative consensus-adaptive weighting (CAW) method. This method permits the dynamic adjustment of multiple deep networks, bolstering the system’s detection capabilities. Our approach also addresses a major challenge in pixel-level data annotation of faster R-CNNs, highlighted in a prominent previous study. Evaluations on various datasets, including the cropped DDSM (Digital Database for Screening Mammography), DDSM, and INbreast, demonstrated the system’s superior performance. In particular, our CAD system showed marked improvement on the cropped DDSM dataset, enhancing detection rates by approximately 1.59% and achieving an accuracy of 95.48%. This innovative system represents a significant advancement in early breast cancer detection, offering the potential for more precise and timely diagnosis, ultimately fostering improved patient outcomes.

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Computer Graphics and Computer-Aided Design,Computer Vision and Pattern Recognition,Radiology, Nuclear Medicine and imaging

Reference63 articles.

1. World Health Organization (2018). International Agency for Research on Cancer, World Health Organization.

2. The impact of mammographic screening on breast cancer mortality in Europe: A review of trend studies;Moss;J. Med. Screen.,2012

3. Breast-cancer tumor size, overdiagnosis, and mammography screening effectiveness;Welch;N. Engl. J. Med.,2016

4. The randomized trials of breast cancer screening: What have we learned?;Smith;Radiol. Clin.,2004

5. Ponti, A., Anttila, A., Ronco, G., and Senore, C. (2017). Cancer Screening in the European Union (2017), World Health Organization. Report on the Implementation of the Council Recommendation on Cancer Screening.

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