Convolutional Neural Network Model for Segmentation and Classification of Clear Cell Renal Cell Carcinoma Based on Multiphase CT Images

Author:

Bolocan Vlad-Octavian12,Secareanu Mihaela2,Sava Elena2,Medar Cosmin12ORCID,Manolescu Loredana Sabina Cornelia1ORCID,Cătălin Rașcu Alexandru-Ștefan34,Costache Maria Glencora1,Radavoi George Daniel34,Dobran Robert-Andrei5,Jinga Viorel346ORCID

Affiliation:

1. Department of Fundamental Sciences, Faculty of Midwifery and Nursing, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania

2. Department of Clinical Laboratory of Radiology and Medical Imaging, Clinical Hospital “Prof. Dr. Theodor Burghele”, 050664 Bucharest, Romania

3. Department of Urology, Clinical Hospital “Prof. Dr. Theodor Burghele”, Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania

4. Department of Urology, Clinical Hospital “Prof. Dr. Theodor Burghele”, 050664 Bucharest, Romania

5. Software Imagination & Vision (Simavi), 013685 Bucharest, Romania

6. Medical Sciences Section, Academy of Romanian Scientists, 050085 Bucharest, Romania

Abstract

(1) Background: Computed tomography (CT) imaging challenges in diagnosing renal cell carcinoma (RCC) include distinguishing malignant from benign tissues and determining the likely subtype. The goal is to show the algorithm’s ability to improve renal cell carcinoma identification and treatment, improving patient outcomes. (2) Methods: This study uses the European Deep-Health toolkit’s Convolutional Neural Network with ECVL, (European Computer Vision Library), and EDDL, (European Distributed Deep Learning Library). Image segmentation utilized U-net architecture and classification with resnet101. The model’s clinical efficiency was assessed utilizing kidney, tumor, Dice score, and renal cell carcinoma categorization quality. (3) Results: The raw dataset contains 457 healthy right kidneys, 456 healthy left kidneys, 76 pathological right kidneys, and 84 pathological left kidneys. Preparing raw data for analysis was crucial to algorithm implementation. Kidney segmentation performance was 0.84, and tumor segmentation mean Dice score was 0.675 for the suggested model. Renal cell carcinoma classification was 0.885 accurate. (4) Conclusion and key findings: The present study focused on analyzing data from both healthy patients and diseased renal patients, with a particular emphasis on data processing. The method achieved a kidney segmentation accuracy of 0.84 and mean Dice scores of 0.675 for tumor segmentation. The system performed well in classifying renal cell carcinoma, achieving an accuracy of 0.885, results which indicates that the technique has the potential to improve the diagnosis of kidney pathology.

Funder

European Union’s Horizon 2020 research and innovation programme

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Computer Graphics and Computer-Aided Design,Computer Vision and Pattern Recognition,Radiology, Nuclear Medicine and imaging

Reference37 articles.

1. WHO/ISUP classification, grading and pathological staging of renal cell carcinoma: Standards and controversies;Warren;World J. Urol.,2018

2. Epidemiology of Renal Cell Carcinoma;Capitanio;Eur. Urol.,2019

3. Epidemiology of Renal Cell Carcinoma;Padala;World J. Oncol.,2020

4. Artificial intelligence for renal cancer: From imaging to histology and beyond;Kowalewski;Asian J. Urol.,2022

5. Surveillance strategies for renal cell carcinoma patients following nephrectomy;Chin;Rev. Urol.,2006

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3