Artificial Intelligence (AI) and Nuclear Features from the Fine Needle Aspirated (FNA) Tissue Samples to Recognize Breast Cancer

Abstract

Breast cancer is one of the paramount causes of new cancer cases worldwide annually. It is a malignant neoplasm that develops in the breast cells. The early screening of this disease is essential to prevent its metastasis. A mammogram X-ray image is the most common screening tool practiced currently when this disease is suspected; all the breast lesions identified are not malignant. The invasive fine needle aspiration (FNA) of a breast mass sample is the secondary screening tool to clinically examine cancerous lesions. The visual image analysis of the stained aspirated sample imposes a challenge for the cytologist to identify the malignant cells accurately. The formulation of an artificial intelligence-based objective technique on top of the introspective assessment is essential to avoid misdiagnosis. This paper addresses several artificial intelligence (AI)-based techniques to diagnose breast cancer from the nuclear features of FNA samples. The Wisconsin Breast Cancer dataset (WBCD) from the UCI machine learning repository is applied for this investigation. Significant statistical parameters are measured to evaluate the performance of the proposed techniques. The best detection accuracy of 98.10% is achieved with a two-layer feed-forward neural network (FFNN). Finally, the developed algorithm’s performance is compared with some state-of-the-art works in the literature.