Calcium, Phosphorus and Magnesium Abnormalities Associated with COVID-19 Infection, and Beyond

Author:

Anghel Lucreția12,Manole Corina12,Nechita Aurel13,Tatu Alin Laurențiu145ORCID,Ștefănescu Bogdan Ioan26ORCID,Nechita Luiza12,Bușilă Camelia13,Zainea Pușica7,Baroiu Liliana14,Mușat Carmina Liana28

Affiliation:

1. Clinical Medical Department, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos’ University, 800008 Galati, Romania

2. ‘Sf. Apostol Andrei’ Clinical Emergency County Hospital, 800578 Galati, Romania

3. ‘Sf. Ioan’ Clinical Hospital for Children, 800487 Galati, Romania

4. ‘Sf. Cuv. Parascheva’ Clinical Hospital of Infectious Diseases, 800179 Galati, Romania

5. Multidisciplinary Integrated Center of Dermatological Interface Research MIC-DIR, 800010 Galati, Romania

6. Clinical Surgery Department, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos’ University, 800008 Galati, Romania

7. Clinical Emergency County Hospital Braila, 810318 Braila, Romania

8. Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos’ University, 800008 Galati, Romania

Abstract

The coronavirus disease (COVID-19) pandemic caused by the novel coronavirus SARS-CoV-2 has had a profound impact on global health, leading to a surge in research to better understand the pathophysiology of the disease. Among the various aspects under investigation, disruptions in mineral homeostasis have emerged as a critical area of interest. This review aims to provide an overview of the current evidence linking calcium, phosphorus and magnesium abnormalities with COVID-19 infection and explores the potential implications beyond the acute phase of the disease. Beyond the acute phase of COVID-19, evidence suggests a potential impact of these mineral abnormalities on long-term health outcomes. Persistent alterations in calcium, phosphorus and magnesium levels have been linked to increased cardiovascular risk, skeletal complications and metabolic disorders, warranting continuous monitoring and management in post-COVID-19 patients.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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