The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study

Author:

Faur Flaviu Ionut12,Clim Ioana Adelina3,Dobrescu Amadeus12ORCID,Isaic Alexandru12,Prodan Catalin12,Florea Sabrina4,Tarta Cristi12ORCID,Totolici Bogdan56,Duţă Ciprian12,Pasca Paul1,Lazar Gabriel78

Affiliation:

1. IInd Surgery Clinic, Timisoara Emergency County Hospital, 300723 Timișoara, Romania

2. Department X of General Surgery, “Victor Babes” University of Medicine and Pharmacy, 300041 Timișoara, Romania

3. IInd Obstetric and Gynecology Clinic “Dominic Stanca”, 400124 Cluj-Napoca, Romania

4. Central Military Emergency University Hospital “Dr. Carol Davila”, 010825 Bucharest, Romania

5. Ist Clinic of General Surgery, Arad County Emergency Clinical Hospital, 310158 Arad, Romania

6. Department of General Surgery, Faculty of Medicine, “Vasile Goldiș” Western University of Arad, 310025 Arad, Romania

7. Department of Oncology Surgery, “Iuliu Hatieganu” University of Medicine and Pharmacy, 400347 Cluj-Napoca, Romania

8. Ist Clinic of Oncological Surgery, Oncological Institute “Prof Dr I Chiricuta” Cluj-Napoca, 400015 Cluj-Napoca, Romania

Abstract

(1) Background: The present study aims to evaluate the reduction of postoperative pain in breast surgery using a series of local analgesics, which were infiltrated into the wound; (2) Methods: Envelopes containing allocation were prepared prior to the study. The patients involved were randomly assigned to the groups of local anesthesia infiltration (Group A) or normal pain management with intravenous analgesics (Group B). The random allocation sequence was generated using computer-generated random numbers. The normally distributed continuous data were expressed as the means (SD) and were assessed using the analysis of variance (ANOVA), independent-sample t-test, or paired t-test; (3) Results: The development of the postoperative pain stages was recorded using the VAS score. Therefore, for Group A, the following results were obtained: the VAS at 6 h postoperatively showed an average value of 0.63 and a maximum value of 3. The results for Group B were the following: the VAS score at 6 h postoperatively showed an average value of 4.92, a maximum of 8, and a minimum of 2; (4) Conclusions: We can confirm that there are favorable statistical indicators regarding the postoperative pain management process during the first 24–38 h after a surgical intervention for breast cancer using local infiltration of anesthetics.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

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