Essential Oils: Chemistry and Pharmacological Activities—Part II

Author:

de Sousa Damião Pergentino1ORCID,de Assis Oliveira Francisco2ORCID,Arcanjo Daniel Dias Rufino3ORCID,da Fonsêca Diogo Vilar4ORCID,Duarte Allana Brunna S.1ORCID,de Oliveira Barbosa Celma3ORCID,Ong Thomas Prates56,Brocksom Timothy John7

Affiliation:

1. Laboratory of Pharmaceutical Chemistry, Federal University of Paraíba, João Pessoa 58051-900, Brazil

2. Medicinal Plants Research Center, Federal University of Piauí, Teresina 64049-550, Brazil

3. LAFMOL—Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piaui, Teresina 64049-550, Brazil

4. Collegiate of Medicine, Federal University of São Francisco Valley, Bahia 48607-190, Brazil

5. Department of Food Science and Nutrition, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo 05508-000, Brazil

6. Food Research Center (FoRC), University of São Paulo, São Paulo 05508-000, Brazil

7. Department of Chemistry, Federal University of São Carlos, São Carlos 13565-905, Brazil

Abstract

The importance of essential oils and their components in the industrial sector is attributed to their chemical characteristics and their application in the development of products in the areas of cosmetology, food, and pharmaceuticals. However, the pharmacological properties of this class of natural products have been extensively investigated and indicate their applicability for obtaining new drugs. Therefore, this review discusses the use of these oils as starting materials to synthesize more complex molecules and products with greater commercial value and clinic potential. Furthermore, the antiulcer, cardiovascular, and antidiabetic mechanisms of action are discussed. The main mechanistic aspects of the chemopreventive properties of oils against cancer are also presented. The data highlight essential oils and their derivatives as a strategic chemical group in the search for effective therapeutic agents against various diseases.

Publisher

MDPI AG

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