Is There a Connection between Hyperhomocysteinemia and the Cardiometabolic Syndrome?

Author:

Tarcau Bogdan Mihai1,Negru Andra2ORCID,Ghitea Timea Claudia3ORCID,Marian Eleonora2ORCID

Affiliation:

1. Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, Romania

2. Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400347 Cluj-Napoca, Romania

3. Pharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania

Abstract

This study investigates the distribution of hyperhomocysteinemia and cardiovascular metabolic syndrome (SM) among participants, shedding light on their prevalence and co-occurrence within the study cohort. Through an analysis of demographic characteristics and health parameters, including age, gender, and body mass index (BMI), alongside nutritional data, correlations between these factors and health risks are explored. Results reveal a notable prevalence of hyperhomocysteinemia, with 45.3% of participants exhibiting this condition. Furthermore, 31.4% of the cohort does not present hyperhomocysteinemia or SM, while 23.3% shows SM without hyperhomocysteinemia. The study underscores gender-specific dietary recommendations due to significant variations in nutrient intake patterns. Additionally, inverse correlations between health risks like obesity, hypertension, and hypercholesterolemia and nutrient requirements highlight the need for tailored dietary interventions. Age-related changes in nutrient needs and the positive correlation between physical activity levels and certain nutrient demands further emphasize the importance of personalized dietary strategies. Variations in nutrient intake by gender, inverse correlations with health risks, and age-related changes underscore the need for tailored dietary strategies. These findings provide valuable insights for healthcare professionals in developing targeted nutritional interventions to mitigate disease risk and promote overall health and well-being.

Funder

University of Oradea

Publisher

MDPI AG

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