FDG and Non-FDG Radiopharmaceuticals for PET Imaging in Invasive Lobular Breast Carcinoma-Reference-Cited by-同舟云学术

FDG and Non-FDG Radiopharmaceuticals for PET Imaging in Invasive Lobular Breast Carcinoma

Published:2023-05-03 Issue:5 Volume:11 Page:1350
ISSN:2227-9059
Container-title:Biomedicines
language:en
Short-container-title:Biomedicines

Author:

Gilardi Laura¹,Airò Farulla Lighea Simona¹²^ORCID,Curigliano Giuseppe²³^ORCID,Corso Giovanni²⁴⁵^ORCID,Leonardi Maria Cristina⁶,Ceci Francesco¹²^ORCID

Affiliation:

1. Division of Nuclear Medicine, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

2. Department of Oncology and Hemato-Oncology, University of Milan, 20122 Milan, Italy

3. Division of New Drugs and Early Drug Development, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

4. Division of Breast Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy

5. European Cancer Prevention Organization (ECP), 20122 Milan, Italy

6. Division of Radiotherapy, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy

Abstract

Invasive lobular cancer (ILC) is the second most frequent histological type of breast cancer (BC) and includes a heterogeneous spectrum of diseases with unique characteristics, especially the infiltrative growth pattern and metastatic spread. [18F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) is extensively used in oncology and BC patient evaluation. Its role in ILCs is considered suboptimal due to its low FDG avidity. Therefore, ILCs could benefit from molecular imaging with non-FDG tracers that target other specific pathways, contributing to precision medicine. This narrative review aims to summarize the current literature on the use of FDG-PET/CT in ILC and to discuss future opportunities given by the development of innovative non-FDG radiotracers.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

Link

https://www.mdpi.com/2227-9059/11/5/1350/pdf

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