The Role of Autophagy in Breast Cancer Metastasis-Reference-Cited by-同舟云学术

The Role of Autophagy in Breast Cancer Metastasis

Published:2023-02-18 Issue:2 Volume:11 Page:618
ISSN:2227-9059
Container-title:Biomedicines
language:en
Short-container-title:Biomedicines

Author:

Kim Hye Min¹,Koo Ja Seung²^ORCID

Affiliation:

1. Department of Pathology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin 16995, Republic of Korea

2. Department of Pathology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea

Abstract

Patient morbidity and mortality is significantly increased in metastatic breast cancer. The metastasis process of breast cancer is very complicated and is delicately controlled by various factors. Autophagy is one of the important regulatory factors affecting metastasis in breast cancer by engaging in cell mobility, metabolic adaptation, tumor dormancy, and cancer stem cells. Here, we discuss the effects of autophagy on metastasis in breast cancer and assess the potential use of autophagy modulators for metastasis treatment.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

Link

https://www.mdpi.com/2227-9059/11/2/618/pdf

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