A Comprehensive Review on Monkeypox Viral Disease with Potential Diagnostics and Therapeutic Options-Reference-Cited by-同舟云学术

A Comprehensive Review on Monkeypox Viral Disease with Potential Diagnostics and Therapeutic Options

Published:2023-06-26 Issue:7 Volume:11 Page:1826
ISSN:2227-9059
Container-title:Biomedicines
language:en
Short-container-title:Biomedicines

Author:

Rabaan Ali A.¹²³^ORCID,Al-Shwaikh Seham A.⁴,Alfouzan Wadha A.⁵⁶^ORCID,Al-Bahar Ali M.⁷,Garout Mohammed⁸,Halwani Muhammad A.⁹,Albayat Hawra¹⁰,Almutairi Norah B.¹⁰,Alsaeed Mohammed¹¹^ORCID,Alestad Jeehan H.¹²¹³,Al-Mozaini Maha A.¹⁴^ORCID,Ashgar Tala M. Al¹⁵,Alotaibi Sultan¹⁶,Abuzaid Abdulmonem A.¹⁷,Aldawood Yahya¹⁸,Alsaleh Abdulmonem A.¹⁸,Al-Afghani Hani M.¹⁹²⁰,Altowaileb Jaffar A.²¹,Alshukairi Abeer N.²²²,Arteaga-Livias Kovy²³²⁴^ORCID,Singh Kirnpal Kaur Banga²⁵^ORCID,Imran Mohd²⁶^ORCID

Affiliation:

1. Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia

2. College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia

3. Department of Public Health and Nutrition, The University of Haripur, Haripur 22610, Pakistan

4. Department of Commitment Management, Directorate of Health Affairs in the Eastern Province, Dammam 31176, Saudi Arabia

5. Department of Microbiology, Faculty of Medicine, Kuwait University, Safat 13110, Kuwait

6. Microbiology Unit, Department of Laboratories, Farwania Hospital, Farwania 85000, Kuwait

7. Department of Laboratory, Dhahran Long Term Care Hospital, Dhahran 34257, Saudi Arabia

8. Department of Community Medicine and Health Care for Pilgrims, Faculty of Medicine, Umm Al-Qura University, Makkah 21955, Saudi Arabia

9. Department of Medical Microbiology, Faculty of Medicine, Al Baha University, Al Baha 4781, Saudi Arabia

10. Infectious Disease Department, King Saud Medical City, Riyadh 7790, Saudi Arabia

11. Infectious Disease Division, Department of Medicine, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia

12. Immunology and Infectious Microbiology Department, University of Glasgow, Glasgow G1 1XQ, UK

13. Microbiology Department, Collage of Medicine, Jabriya 46300, Kuwait

14. Immunocompromsised Host Research Section, Department of Infection and Immunity, King Faisal, Specialist Hospital and Research Centre, Riyadh 11564, Saudi Arabia

15. College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh 11481, Saudi Arabia

16. Molecular Microbiology Department, King Fahad Medical City, Riyadh 11525, Saudi Arabia

17. Medical Microbiology Department, Security Forces Hospital Programme, Dammam 32314, Saudi Arabia

18. Clinical Laboratory Science Department, Mohammed Al-Mana College for Medical Sciences, Dammam 34222, Saudi Arabia

19. Laboratory Department, Security Forces Hospital, Makkah 24269, Saudi Arabia

20. iGene Center for Research and Training, Jeddah 2022, Saudi Arabia

21. Microbiology Laboratory, Laboratory Department, Qatif Central Hospital, Qatif 32654, Saudi Arabia

22. Department of Medicine, King Faisal Specialist Hospital and Research Center, Jeddah 22233, Saudi Arabia

23. Escuela de Medicina-Filial Ica, Universidad Privada San Juan Bautista, Ica 11000, Peru

24. Escuela de Medicina, Universidad Nacional Hermilio Valdizán, Huanuco 10000, Peru

25. Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia

26. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha 91911, Saudi Arabia

Abstract

The purpose of this review is to give an up-to-date, thorough, and timely overview of monkeypox (Mpox), a severe infectious viral disease. Furthermore, this review provides an up-to-date treatment option for Mpox. The monkeypox virus (MPXV) has remained the most virulent poxvirus for humans since the elimination of smallpox approximately 41 years ago, with distribution mainly in central and west Africa. Mpox in humans is a zoonotically transferred disease that results in symptoms like those of smallpox. It had spread throughout west and central Africa when it was first diagnosed in the Republic of Congo in 1970. Mpox has become a major threat to global health security, necessitating a quick response by virologists, veterinarians, public health professionals, doctors, and researchers to create high-efficiency diagnostic tests, vaccinations, antivirals, and other infection control techniques. The emergence of epidemics outside of Africa emphasizes the disease’s global significance. A better understanding of Mpox’s dynamic epidemiology may be attained by increased surveillance and identification of cases.

Publisher

MDPI AG

Subject

General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

Link

https://www.mdpi.com/2227-9059/11/7/1826/pdf

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