Targeting the HIV-1 and HBV Capsids, an EnCore

Author:

McFadden William M.12ORCID,Sarafianos Stefan G.12

Affiliation:

1. Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA

2. Children’s Healthcare of Atlanta, Atlanta, GA 30322, USA

Abstract

Not many structures are common among all viruses: only nucleic acid and a protein coat [...]

Funder

National Institutes of Health

Nahmias-Schinazi Distinguished Chair in Research

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

Reference24 articles.

1. Viral structural proteins as targets for antivirals;Schlicksup;Curr. Opin. Virol.,2020

2. Viruses Defined by the Position of the Virosphere within the Replicator Space;Koonin;Microbiol. Mol. Biol. Rev.,2021

3. Taverniti, V., Ligat, G., Debing, Y., Kum, D.B., Baumert, T.F., and Verrier, E.R. (2022). Capsid Assembly Modulators as Antiviral Agents against HBV: Molecular Mechanisms and Clinical Perspectives. J. Clin. Med., 11.

4. Formation of a Human Immunodeficiency Virus Type 1 Core of Optimal Stability Is Crucial for Viral Replication;Forshey;J. Virol.,2002

5. U.S. Food and Drug Administration (2023, March 23). FDA Approves New HIV Drug for Adults with Limited Treatment Options, Available online: https://www.fda.gov/news-events/press-announcements/fda-approves-new-hiv-drug-adults-limited-treatment-options.

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