On the Various Numerical Techniques for the Optimization of Bone Scaffold

Author:

Wu Jiongyi1,Zhang Youwei1,Lyu Yongtao12ORCID,Cheng Liangliang3

Affiliation:

1. Department of Engineering Mechanics, Dalian University of Technology, No. 2 Linggong Road, Dalian 116024, China

2. State Key Laboratory of Structural Analysis for Industrial Equipment, Dalian University of Technology, No. 2 Linggong Road, Dalian 116024, China

3. Department of Orthopeadics, Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Dalian 116001, China

Abstract

As the application of bone scaffolds becomes more and more widespread, the requirements for the high performance of bone scaffolds are also increasing. The stiffness and porosity of porous structures can be adjusted as needed, making them good candidates for repairing damaged bone tissues. However, the development of porous bone structures is limited by traditional manufacturing methods. Today, the development of additive manufacturing technology has made it very convenient to manufacture bionic porous bone structures as needed. In the present paper, the current state-of-the-art optimization techniques for designing the scaffolds and the settings of different optimization methods are introduced. Additionally, various design methods for bone scaffolds are reviewed. Furthermore, the challenges in designing high performance bone scaffolds and the future developments of bone scaffolds are also presented.

Funder

the National Natural Science Foundation of China

the Liaoning Provincial Natural Science Foundation of China

the Dalian Science and Technology Innovation Fund

the open fund from the State Key Laboratory of Structural Analysis for Industrial Equipment

Publisher

MDPI AG

Subject

General Materials Science

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5. Bone Morphogenetic Proteins in Orthopedics: From Basic Science to Clinical Practice;Croteau;Orthop. (Thorofare N.J.),1999

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