Hydrofluoric Acid-Free Digestion of Organosilicon Nanoparticles for Bioanalysis by ICP-OES

Author:

Yousefpour Nooshin1,Björnberg Olof1,Yao Mattisson Ingrid1ORCID,Axelsson Oskar1

Affiliation:

1. Spago Nanomedical AB, Scheelevägen 22, 223 63 Lund, Sweden

Abstract

A novel ICP-OES method has been developed for the determination of Si concentration, originating from polyorganophosphosilanes, in biological specimens that also contain metal ions. The method is free of hazardous hydrofluoric acid (HF) and involves digestion with HNO3/H2O2 prior to the analysis by ICP-OES. High and reproducible spike recovery was obtained from the controls.

Publisher

MDPI AG

Subject

Earth-Surface Processes

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