Current Applications and New Perspectives in Optical Coherence Tomography (OCT) Coronary Atherosclerotic Plaque Assessment: From PCI Optimization to Pharmacological Treatment Guidance
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Published:2023-02-02
Issue:2
Volume:10
Page:158
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ISSN:2304-6732
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Container-title:Photonics
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language:en
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Short-container-title:Photonics
Author:
Viscusi Michele Mattia1, La Porta Ylenia1ORCID, Migliaro Giuseppe1, Gargano Gian Marco1, Nusca Annunziata1, Gatto Laura2, Budassi Simone2, Paolucci Luca1, Mangiacapra Fabio1, Ricottini Elisabetta1, Melfi Rosetta1, Rinaldi Raffaele1, Prati Francesco23, Ussia Gian Paolo1, Grigioni Francesco1
Affiliation:
1. Unit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, 00128 Rome, Italy 2. San Giovanni Addolorata Hospital, Cardiology Department, 00184 Rome, Italy 3. Faculty of Medicine and Surgery, Unicamillus-Saint Camillus International University of Health Sciences, 00131 Rome, Italy
Abstract
Since its ability to precisely characterized atherosclerotic plaque phenotypes, to tailor stent implantation, as well as to guide both complex percutaneous coronary interventions (PCI) and invasive diagnostic work-ups (e.g., spontaneous coronary dissections or myocardial infarction with non-obstructive arteries), the adoption of optical coherence tomography (OCT) was raised in the past decades in order to provide complementary information to the traditional angiography and to overcome its limitations. However, the impact of OCT on daily clinical practice is currently modest, firstly because of the lack of both standardized algorithms of PCI guidance and data from prospective clinical trials. Therefore, the aim of our narrative review is to provide a comprehensive overview of the basic OCT interpretation, to summarize the evidence supporting the OCT guidance procedures and applications, to discuss its current limitations, and to highlight the knowledge gaps that need to be filled with more robust evidence.
Subject
Radiology, Nuclear Medicine and imaging,Instrumentation,Atomic and Molecular Physics, and Optics
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