Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach-Reference-Cited by-同舟云学术

Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach

Published:2024-05-30 Issue:6 Volume:22 Page:256
ISSN:1660-3397
Container-title:Marine Drugs
language:en
Short-container-title:Marine Drugs

Author:

Gill Richa¹^ORCID,Al-Badr Mashael¹,Alghouti Mohammad²^ORCID,Mohamed Nura Adam³,Abou-Saleh Haissam⁴^ORCID,Rahman Md Mizanur¹^ORCID

Affiliation:

1. Biological Science Program, Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, Doha P.O. Box 2713, Qatar

2. Environmental Science Program, Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, Doha P.O. Box 2713, Qatar

3. Biomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar

4. Biomedical Sciences Department, College of Health Sciences, Qatar University, Doha P.O. Box 2713, Qatar

Abstract

Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) offer diverse health benefits, such as supporting cardiovascular health, improving cognitive function, promoting joint and musculoskeletal health, and contributing to healthy aging. Despite their advantages, challenges like oxidation susceptibility, low bioavailability, and potential adverse effects at high doses persist. Nanoparticle encapsulation emerges as a promising avenue to address these limitations while preserving stability, enhanced bioavailability, and controlled release. This comprehensive review explores the therapeutic roles of omega-3 fatty acids, critically appraising their shortcomings and delving into modern encapsulation strategies. Furthermore, it explores the potential advantages of metal–organic framework nanoparticles (MOF NPs) compared to other commonly utilized nanoparticles in improving the therapeutic effectiveness of omega-3 fatty acids within drug delivery systems (DDSs). Additionally, it outlines future research directions to fully exploit the therapeutic benefits of these encapsulated omega-3 formulations for cardiovascular disease treatment.

Funder

Qatar University

Publisher

MDPI AG

Link

https://www.mdpi.com/1660-3397/22/6/256/pdf

Reference153 articles.

1. Heart Disease and Stroke Statistics—2023 Update: A Report from the American Heart Association;Tsao;Circulation,2023

2. National Center for Health Statistics (2024, January 02). Multiple Cause of Death Data on CDC WONDER, Available online: https://wonder.cdc.gov/mcd.html.

3. World Health Organization (2024, January 02). Cardiovascular Diseases (CVDs). Available online: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds).

4. Centers for Disease Control and Prevention (2024, January 02). Heart Disease and Stroke, Available online: https://www.cdc.gov/heart-disease/data-research/facts-stats/index.html.

5. American Heart Association (2024, January 02). Consuming about 3 Grams of Omega-3 Fatty Acids a Day May Lower Blood Pressure. Available online: https://www.heart.org/en/news/2022/06/01/consuming-about-3-grams-of-omega-3-fatty-acids-a-day-may-lower-blood-pressure.