Cardiovascular Applications of Photon-Counting CT Technology: A Revolutionary New Diagnostic Step

Author:

Meloni Antonella12ORCID,Cademartiri Filippo1ORCID,Positano Vicenzo12ORCID,Celi Simona3ORCID,Berti Sergio4ORCID,Clemente Alberto1ORCID,La Grutta Ludovico5,Saba Luca6,Bossone Eduardo7ORCID,Cavaliere Carlo8ORCID,Punzo Bruna8,Maffei Erica1

Affiliation:

1. Department of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy

2. Unità Operativa Complessa di Bioingegneria, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy

3. BioCardioLab, Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy

4. Diagnostic and Interventional Cardiology Department, Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy

5. Department of Radiology, University Hospital “P. Giaccone”, 90127 Palermo, Italy

6. Department of Radiology, University Hospital of Cagliari, 09042 Monserrato, CA, Italy

7. Department of Cardiology, Ospedale Cardarelli, 80131 Naples, Italy

8. Department of Radiology, Istituto di Ricerca e Cura a Carattere Scientifico SynLab-SDN, 80131 Naples, Italy

Abstract

Photon-counting computed tomography (PCCT) is an emerging technology that can potentially transform clinical CT imaging. After a brief description of the PCCT technology, this review summarizes its main advantages over conventional CT: improved spatial resolution, improved signal and contrast behavior, reduced electronic noise and artifacts, decreased radiation dose, and multi-energy capability with improved material discrimination. Moreover, by providing an overview of the existing literature, this review highlights how the PCCT benefits have been harnessed to enhance and broaden the diagnostic capabilities of CT for cardiovascular applications, including the detection of coronary artery calcifications, evaluation of coronary plaque extent and composition, evaluation of coronary stents, and assessment of myocardial tissue characteristics and perfusion.

Publisher

MDPI AG

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

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