Sudden Infant Death Associated with Rhinovirus Infection

Author:

Auvray Christelle1,Perez-Martin Stéphanie2,Schuffenecker Isabelle3,Pitoiset Cécile1,Tarris Georges4,Ambert-Balay Katia5,Martin Laurent4,Dullier-Taillefumier Nathalie4,Bour Jean-Baptiste1,Manoha Catherine1ORCID

Affiliation:

1. Department of Microbiology, Virology Laboratory, Dijon University Hospital, 21070 Dijon, France

2. Department of Pediatrics, Dijon University Hospital, 21079 Dijon, France

3. French National Enterovirus/Parechovirus Reference Centre, Hospices Civils de Lyon, 69317 Lyon, France

4. Department of Pathology, Dijon University Hospital, 21070 Dijon, France

5. French National Reference Centre for Gastroenteritis Viruses, Virology Laboratory, University Hospital of Dijon, 21070 Dijon, France

Abstract

A less than one-month-old infant with symptoms of rhinitis died unexpectedly in his sleep. He was not born prematurely and had no known underlying disease. Cerebrospinal fluid, nasopharyngeal and lung samples, and rectal swab were found to be positive for subgroup A rhinovirus, while the blood was negative. This case highlights the important finding that the rhinovirus, a common pathogen associated with upper respiratory tract infections, can sometimes, as the only pathogen, lead to complications such as a cerebrospinal infection and be involved in the sudden infant death syndrome (SIDS). Vigilance is necessary in case of viral infections in the infant’s environment, and measures of hygiene and protection must be encouraged in order to reduce the risk of the SIDS.

Publisher

MDPI AG

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