Spinal Involvement in Patients with Chronic Non-Bacterial Osteomyelitis (CNO): An Analysis of Distinctive Imaging Features

Author:

Byrdy-Daca Marta1ORCID,Duczkowski Marek2,Sudoł-Szopińska Iwona3ORCID,Żelewska Marta4,Piłat Krzysztof14,Daca Filip5,Nieciecki Michał3,Sztwiertnia Paweł4,Walecki Jerzy4,Cieszanowski Andrzej6,Świątkowski Jan14,Bereźniak Marlena1,Sułkowska Katarzyna1,Czubak Jarosław4,Gołębiowski Marek1,Palczewski Piotr14

Affiliation:

1. I Department of Clinical Radiology, Medical University of Warsaw, 02-091 Warsaw, Poland

2. Department of Diagnostic Imaging, Institute of Mother and Child, 01-211 Warsaw, Poland

3. Department of Radiology, The National Institute of Geriatrics, Rheumatology and Rehabilitation, 02-637 Warsaw, Poland

4. Gruca Orthopaedic and Trauma Teaching Hospital, Center of Postgraduate Medical Education, 05-400 Otwock, Poland

5. Independent Researcher, 00-195 Warszawa, Poland

6. The Maria Skłodowska Curie Memorial Cancer Centre and Institute of Oncology, 05-077 Warsaw, Poland

Abstract

Spinal involvement by chronic non-bacterial osteomyelitis (CNO) has been increasingly reported in recent years, often being presented as a diagnostic dilemma requiring differential diagnosis with bacterial spondylodiscitis and/or neoplasia. This study was aimed at identifying the imaging features of CNO facilitating its differentiation from other spinal diseases. Two radiologists assessed the imaging studies of 45 patients (16 male and 29 female, aged from 6 to 75 years, 15 children) with CNO collected from 5 referential centers. Spinal lesions were found in 17 patients (2 children and 15 adults), most often in the thoracic spine. In children, the lesions involved short segments with a destruction of vertebral bodies. In adults, the main findings were prominent bone marrow edema and osteosclerosis, endplate irregularities, and ankylosing lesions extending over long segments; paraspinal inflammation was mild and abscesses were not observed. In both children and adults, the involvement of posterior elements (costovertebral and facet joints) emerged as an important discriminator between CNO and neoplasia/other inflammatory conditions. In conclusion, a careful inspection of imaging studies may help to reduce the number of biopsies performed in the diagnostic process of CNO.

Publisher

MDPI AG

Subject

General Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3