Does Music Intervention Improve Anxiety in Dementia Patients? A Systematic Review and Meta-Analysis of Randomized Controlled Trials-Reference-Cited by-同舟云学术

Does Music Intervention Improve Anxiety in Dementia Patients? A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Published:2023-08-24 Issue:17 Volume:12 Page:5497
ISSN:2077-0383
Container-title:Journal of Clinical Medicine
language:en
Short-container-title:JCM

Author:

Ting Berne¹²^ORCID,Chen Daniel Tzu-Li²³⁴⁵^ORCID,Hsu Wei-Ti⁵⁶^ORCID,Liang Chih-Sung⁷^ORCID,Malau Ikbal Andrian²⁵^ORCID,Li Wei-Chih²⁸^ORCID,Lee Sheau-Ling⁹,Jingling Li⁵^ORCID,Su Kuan-Pin²⁵¹⁰^ORCID

Affiliation:

1. Ph.D. Program for Aging, College of Medicine, China Medical University, Taichung 40402, Taiwan

2. Mind–Body Interface Laboratory (MBI-Lab), China Medical University Hospital, Taichung 40402, Taiwan

3. M.D.-Ph.D. Program, College of Medicine, China Medical University, Taichung 40402, Taiwan

4. School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan

5. Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan

6. Department of Anesthesiology, China Medical University Hospital, Taichung 40402, Taiwan

7. Beitou Branch, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan

8. School of Medicine, College of Medicine, China Medical University, Taichung 40402, Taiwan

9. National Health Research Institutes, Miaoli 35053, Taiwan

10. An-Nan Hospital, China Medical University, Tainan 70965, Taiwan

Abstract

Music interventions (MIs) have been widely used to relieve anxiety in dementia in clinical settings. However, limited meta-analysis with randomized controlled trials (RCTs) on this topic has been conducted so far. A systematic search was conducted in four major databases (PubMed, EMBASE, Web of Science, and Cochrane Library) for data provided by RCTs from the inception to February 2023. The search strategy employed the terms “anxiety AND music AND dementia OR Alzheimer’s disease”. Thirteen RCTs (827 participants) were included. The results showed MI reduced anxiety significantly (SMD = −0.67, p < 0.001), especially for Alzheimer’s disease (p = 0.007) and Mixed (p < 0.001)-type dementia. Moreover, significant improvements in agitation (p = 0.021) and depression (p < 0.001) in dementia were observed. Additionally, several psychological mechanisms which may be associated with MI were reviewed comprehensively. In conclusion, our findings support the efficacy of MI in alleviating anxiety symptoms in dementia patients. PROSPERO Registration (ID: CRD42021276646).

Funder

MOST

National Science and Technology Council, Taiwan

An-Nan Hospital, China Medical University, Tainan, Taiwan

Higher Education Sprout Project by the Ministry of Education (MOE), Taiwan

China Medical University Hospital, Taichung, Taiwan

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2077-0383/12/17/5497/pdf

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