Assessment of the Impact of Trace Essential Metals on Cancer Development

Author:

Górska Aleksandra1ORCID,Markiewicz-Gospodarek Agnieszka1ORCID,Trubalski Mateusz2ORCID,Żerebiec Marta2,Poleszak Julia2ORCID,Markiewicz Renata3

Affiliation:

1. Department of Normal, Clinical and Imaging Anatomy, Medical University of Lublin, 4 Jaczewskiego St., 20-090 Lublin, Poland

2. Students Scientific Association, Department of Normal, Clinical and Imaging Anatomy, Medical University of Lublin, 4 Jaczewskiego St., 20-090 Lublin, Poland

3. Occupational Therapy Laboratory, Chair of Nursing Development, Medical University of Lublin, 4 Staszica St., 20-081 Lublin, Poland

Abstract

This study examines the impact of zinc, copper, cobalt, iron, and manganese on cancer development, considering their dual roles as potential promoters or inhibitors within tumorigenesis. A comprehensive analysis of existing literature and experimental data is conducted to elucidate the intricate relationship between these trace elements and cancer progression. The findings highlight the multifaceted effects of zinc, copper, cobalt, iron, and manganese on various aspects of cancer development, including cell proliferation, angiogenesis, and metastasis. Understanding the nuanced interactions between these trace elements and cancer could offer crucial insights into tumorigenesis mechanisms and facilitate the identification of novel biomarkers and therapeutic targets for cancer prevention and treatment strategies. This research underscores the importance of considering the roles of essential trace elements in cancer biology and may ultimately contribute to advancements in precision medicine approaches for combating cancer.

Publisher

MDPI AG

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