Genome Analysis of Nicotinamide Adenine Dinucleotide-Independent Mycoplasma synoviae Isolates From Korea
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Published:2021-09-23
Issue:10
Volume:10
Page:1231
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ISSN:2076-0817
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Container-title:Pathogens
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language:en
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Short-container-title:Pathogens
Author:
Song Yongjun,La Tae-Min,Kim Taesoo,Ahn Gyuhee,Hur Won,Lee Hong-Jae,Shin Hyunjin,Song Seung-un,Park Eunjin,Lee Joong-Bok,Park Seung-Yong,Choi In-Soo,Lee Sang-Won
Abstract
Mycoplasma synoviae (MS) is an avian pathogen that causes respiratory disease, infectious synovitis, and eggshell apex abnormalities in chickens. Nicotinamide adenine dinucleotide (NAD)-independent MS was first reported in 1975. Despite the atypical traits of NAD-independent MS, its independence from NAD has not been studied. In this study, we isolated five NAD-independent strains from Korea and assembled their genomes using sequencing reads obtained from Illumina and Oxford Nanopore Technology platforms. The assembled genomes were compared with the genomes of MS-H vaccine strain and type strain WVU1853. We found that the coding sequences of nicotinate phosphoribosyltransferase and glycerol-3-phosphate acyltransferase, and a unique coding sequence were present only in the genomes of NAD-independent isolates.
Funder
Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry
Subject
Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,Molecular Biology,Immunology and Allergy
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