Affiliation:
1. Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, 51006 Tartu, Estonia
2. The National Centre for Laboratory Research and Risk Assessment, LABRIS, 51006 Tartu, Estonia
Abstract
The African swine fever virus (ASFV) was first detected in Estonia, in September 2014. In the subsequent three years, the virus spread explosively all over the country. Only one county, the island of Hiiumaa, remained free of the disease. Due to the drastic decrease in the wild boar population in the period of 2015–2018, the number of ASFV-positive cases among wild boar decreased substantially. From the beginning of 2019 to the autumn of 2020, no ASFV-positive wild boar or domestic pigs were detected in Estonia. A new occurrence of ASFV was detected in August 2020, and by the end of 2022, ASFV had been confirmed in seven counties in Estonia. Investigations into proven molecular markers, such as IGR I73R/I329L, MGF505-5R, K145R, O174L, and B602L, were performed with the aim of clarifying whether these cases of ASFV were new entries or remnants of previous epidemics. The sequences from the period of 2014–2022 were compared to the Georgia 2007/1 reference sequence and the variant strains present in Europe. The results indicated that not all the molecular markers of the virus successfully used in other geographical regions were suitable for tracing the spread of ASFV in Estonia. Only the B602L-gene analysis enabled us to place the ASFV isolates spreading in 2020–2022 into two epidemiologically different clusters.
Funder
Estonian University of Life Sciences
Subject
Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,Molecular Biology,Immunology and Allergy
Reference28 articles.
1. ICTV Virus Taxonomy Profile: Asfarviridae;Alonso;J. Gen. Virol.,2018
2. Genetic Variation among African Swine Fever Genotype II Viruses, Eastern and Central Europe;Gallardo;Emerg. Infect. Dis.,2014
3. African Swine Fever: Update on Eastern, Central and Southern Africa;Saegerman;Transbound. Emerg. Dis.,2019
4. Mur, L. (2022). African Swine Fever (Asf)—Situation Report 4, WOAH. AFRICAN SWINE FEVER 6.
5. A Multi Gene-Approach Genotyping Method Identifies 24 Genetic Clusters within the Genotype II-European African Swine Fever Viruses Circulating from 2007 to 2022;Gallardo;Front. Vet. Sci.,2023
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