Mathematical Model of the Spread of Hantavirus Infection

Author:

Gutiérrez-Jara Juan Pablo1ORCID,Muñoz-Quezada María Teresa2ORCID,Córdova-Lepe Fernando3,Silva-Guzmán Alex4

Affiliation:

1. Centro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca 3480112, Chile

2. School of Public Health, Faculty of Medicine, Universidad de Chile, Avenida Independencia 939, Santiago 8320000, Chile

3. Facultad de Ciencias Básicas, Universidad Católica del Maule, Avenida San Miguel 3605, Talca 3480112, Chile

4. Maule Regional Ministerial Health Secretariat, Talca 3480112, Chile

Abstract

A mathematical epidemiological model incorporating the mobility of rodents and human groups among zones of less or major contact between them is presented. The hantavirus infection dynamics is expressed using a model type SEIR (Susceptible-Exposed-Infectious-Removed), which incorporates the displacement of the rodent and the human, between the urban and rural sector, the latter being subdivided in populated and non-populated. The results show the impact that rodent or human displacement may have on the propagation of hantavirus infection. Human mobility is more significant than rodents in increasing the number of hantavirus infection cases. The results found may be used as a reference by the health authorities to develop more specific campaigns on the territorial dynamics of the rodent, attend to the mobility of humans in these territories, mainly agricultural and forestry workers, and strengthen control-prevention actions in the community, to prevent future outbreaks that are fatal.

Publisher

MDPI AG

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,Molecular Biology,Immunology and Allergy

Reference59 articles.

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2. PAHO (2022, June 25). Pan American Health Organization. Hantavirus 2017. Available online: https://www3.paho.org/hq/index.php?option=com_content&view=article&id=14911:hantavirus&Itemid=40721&lang=en.

3. Revisiting the genetic diversity of emerging hantaviruses circulating in Europe using a pan-viral resequencing microarray;Filippone;Sci. Rep.,2019

4. Vaccines and Therapeutics Against Hantaviruses;Liu;Front. Microbiol.,2020

5. Hantavirus: Description of two decades of endemic disease and its lethality;Reyes;ARS MEDICA,2019

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