Exploring the Potential Hepatoprotective Properties of Cactus (Cactaceae) in Liver Health and Disease Management: A Brief Review

Author:

Vieira Anne Caroline Alves12ORCID,Ferreira Fabrícia de Souza13,Araújo Januse Míllia Dantas de12,Dutra Larissa Maria Gomes13ORCID,Batista Kamila Sabino4ORCID,Cordeiro Angela Maria Tribuzy de Magalhães5ORCID,Aquino Jailane de Souza123ORCID

Affiliation:

1. Experimental Nutrition Laboratory, Department of Nutrition, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil

2. Post Graduate Program in Nutrition Sciences, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil

3. Post Graduate Program in Food Science and Technology, Federal University of Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil

4. National Semiarid Institute—INSA/MCTI, Campina Grande 58434-700, PB, Brazil

5. Department of Food Technology, Center of Technology and Regional Development, Federal University of Paraíba (UFPB), João Pessoa 58058-600, PB, Brazil

Abstract

Cacti are renowned for their resilience in arid environments and have been utilized as a valuable food source in various cultures for centuries. The potential effects of cactus (Cactaceae) consumption on liver health have garnered significant scientific interest in recent years. This review aimed to consolidate and analyze existing research findings regarding the relationship between cactus-derived compounds and their influence on liver function and health. Various cactus species, particularly Opuntia spp., are rich reservoirs of antioxidants, polyphenols, flavonoids, and betalains. In vitro and in vivo studies with animal models have shown that bioactive constituents of cactus exhibit anti-inflammatory, antioxidative, and antifibrotic properties, which potentially mitigate liver damage induced by oxidative stress, inflammation, and hepatotoxic agents. Understanding their mechanisms of action and conducting rigorous clinical studies with administration of cactus will ascertain their role in preventing and treating liver ailments, offering novel avenues in nutrition, hepatology, and natural medicine.

Funder

Fundação de Apoio à Pesquisa do Estado da Paraíba—FAPESQ

Conselho Nacional de Desenvolvimento Científico e Tecnológico—CNPq

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—CAPES, Brazil

Publisher

MDPI AG

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