The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases-Reference-Cited by-同舟云学术

The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases

Published:2023-09-12 Issue:18 Volume:24 Page:13977
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Szrok-Jurga Sylwia¹^ORCID,Turyn Jacek¹^ORCID,Hebanowska Areta¹,Swierczynski Julian²,Czumaj Aleksandra³,Sledzinski Tomasz³^ORCID,Stelmanska Ewa¹^ORCID

Affiliation:

1. Department of Biochemistry, Faculty of Medicine, Medical University of Gdansk, 80-211 Gdansk, Poland

2. Institute of Nursing and Medical Rescue, State University of Applied Sciences in Koszalin, 75-582 Koszalin, Poland

3. Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Medical University of Gdansk, 80-211 Gdansk, Poland

Abstract

This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders.

Funder

Medical University of Gdansk

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Link

https://www.mdpi.com/1422-0067/24/18/13977/pdf

Reference93 articles.

1. Brain Glucose Metabolism: Integration of Energetics with Function;Dienel;Physiol. Rev.,2019

2. Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease;Tracey;Front. Mol. Neurosci.,2018

3. Roberts, E.L. (2007). Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics, Springer. Integration of Molecular and Cellular Processes.

4. Loss of Fatty Acid Degradation by Astrocytic Mitochondria Triggers Neuroinflammation and Neurodegeneration;Mi;Nat. Metab.,2023

5. Rapid Uptke of [1-14C] Acetate by the Adult Rat Brain 15 Seconds after Carotid Injection;Dhopeshwarkar;Biochim. Et Biophys. Acta (BBA)/Lipids Lipid Metab.,1971

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