Leptomeningeal Carcinomatosis in Early Gastric Cancer: A Case Report and Literature Review-Reference-Cited by-同舟云学术

Leptomeningeal Carcinomatosis in Early Gastric Cancer: A Case Report and Literature Review

Published:2024-06-12 Issue:12 Volume:12 Page:1184
ISSN:2227-9032
Container-title:Healthcare
language:en
Short-container-title:Healthcare

Author:

Lucarini Alessio¹,Arrivi Giulia²^ORCID,Liotta Elena²,Li Causi Francesco Saverio¹^ORCID,Di Cicco Leonardo¹,Mazzuca Federica²,Osti Mattia Falchetto³^ORCID,Balducci Genoveffa¹,Mercantini Paolo¹

Affiliation:

1. Surgical and Medical Department of Translational Medicine, Sant’Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, 00189 Rome, Italy

2. Oncology Unit, Department of Clinical and Molecular Medicine, Sant’ Andrea University Hospital, Sapienza University of Rome, 00189 Rome, Italy

3. Department of Medicine and Surgery and Translational Medicine, Radiotherapy Oncology, Sapienza University of Rome, Sant’Andrea Hospital, 00189 Rome, Italy

Abstract

Leptomeningeal carcinomatosis (LC) is a rare site of metastasis in solid tumors, and it is associated with poor prognosis due to disabling symptoms and a scarcity of treatment options. This condition is an uncommon entity in gastric cancer (GC). We present a case of primary LC manifestation in a patient with an incidental diagnosis of localized node-negative GC. We additionally perform a literature review and discuss the diagnostic and therapeutic challenges. In conclusion, LC from GC represents a rare condition with a dramatic prognosis. Its diagnosis might be very challenging. A multidisciplinary approach appears to be the best strategy for the management of LC from GC.

Publisher

MDPI AG

Link

https://www.mdpi.com/2227-9032/12/12/1184/pdf

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