Effects of a Multicomponent Preventive Intervention in Women at Risk of Sarcopenia: A Pilot Study

Author:

Rios-Escalante Violeta12ORCID,Perez-Barba Juan Carlos3ORCID,Espinel-Bermudez Maria Claudia1234ORCID,Zavalza-Gomez Ana Bertha3ORCID,Arias-Merino Elva Dolores1ORCID,Zavala-Cerna Maria G.5ORCID,Sanchez-Garcia Sergio6ORCID,Trujillo Xochitl7ORCID,Nava-Zavala Arnulfo Hernan8910ORCID

Affiliation:

1. Departamento de Salud Publica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico

2. Facultad de Medicina, Universidad de Colima, Colima 28040, Colima, Mexico

3. Hospital de Ginecologia y Obstetricia, Centro Medico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44329, Jalisco, Mexico

4. Unidad de Investigacion Biomedica 02, Hospital de Especialidades, Centro Medico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44329, Jalisco, Mexico

5. Unidad Academica Ciencias de la Salud, Universidad Autónoma de Guadalajara, Zapopan 45129, Jalisco, Mexico

6. Unidad de Investigación Epidemiológica y en Servicios de Salud, Area Envejecimiento, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de Mexico 06720, Mexico

7. Centro Universitario de Investigaciones Biomedicas, Universidad de Colima, Colima 28040, Colima, Mexico

8. Unidad de Investigacion Epidemiologica y en Servicios de Salud, Centro Medico Nacional de Occidente Organo de Operación Administrativa Desconcentrada Jalisco, Instituto Mexicano del Seguro Social, Guadalajara 44329, Jalisco, Mexico

9. Programa Internacional de Medicina, Universidad Autónoma de Guadalajara, Zapopan 45129, Jalisco, Mexico

10. Departamento de Inmunologia y Reumatologia del Hospital General de Occidente, Secretaria de Salud Jalisco, Guadalajara 45170, Jalisco, Mexico

Abstract

Sarcopenia is defined by the presence of decreased skeletal muscle mass, strength, and functionality in older people. Multicomponent interventions represent an alternative to non-pharmacological treatment for preventing disease progression. This study aimed to evaluate the effects of a multicomponent intervention approach in women at risk of sarcopenia. Methods: A quasi-experimental pilot study of 12 weeks was conducted, with 24 sessions of dancing and resistance exercises and 12 sessions of nutritional education. The outcomes were changes in muscle mass, grip strength, gait speed, and body composition. The project was registered on Clinical Trials: NCT06038500 (14 September 2023). Results: Twelve women aged 55–75 years participated in this study; after the intervention, changes were found in the following variables: grip strength, from 18.70 (17.98–19.23) at baseline to 21.57 (20.67–23.16) kg (p = 0.002); gait speed, from 0.95 (0.81–1.18) at baseline to 1.34 (1.20–1.47) m/s (p = 0.003); and hip circumference, from 99.75 (94.75–110.37) at baseline to 97.65 (93.92–109.50) cm (p = 0.023). Other measurements that appeared without changes were appendicular skeletal muscle mass, from 21.17 (18.58–22.33) at baseline to 20.77 (18.31–22.39) kg (p = 0.875), and the appendicular skeletal muscle mass index, from 8.64 (8.08–9.35) at baseline to 8.81 (7.91–9.38) kg/m2 (p = 0.875) after the intervention. Conclusions: The three-month multicomponent intervention in women at risk of sarcopenia improved their grip strength and gait speed.

Funder

the National Council of Science and Technology in Mexico

Institucional “Fondo Semilla” from Universidad Autonoma de Guadalajara

UAGs’ Fondo Semilla for Research

Publisher

MDPI AG

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