Parental Factors Associated with Child or Adolescent Medication Adherence: A Systematic Review

Author:

Kalaman Clarisse Roswini1,Ibrahim Norhayati12,Shaker Vinorra3,Cham Choy Qing1ORCID,Ho Meng Chuan4,Visvalingam Uma5,Shahabuddin Farah Ahmad6,Abd Rahman Fairuz Nazri7ORCID,A Halim Mohd Radzi Tarmizi8,Kaur Manveen9,Azhar Fatin Liyana9,Yahya Amira Najiha10ORCID,Sham Rohana11ORCID,Siau Ching Sin12ORCID,Lee Kai Wei13ORCID

Affiliation:

1. Center for Healthy Ageing and Wellness (H-CARE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia

2. Institute of Islam Hadhari, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia

3. School of Psychology, Asia Pacific University of Technology and Innovation, Kuala Lumpur 57000, Malaysia

4. Center for Pre-U Studies, UCSI University, Cheras 56000, Malaysia

5. Department of Psychiatry, Hospital Putrajaya, Putrajaya 62250, Malaysia

6. Department of Psychiatry, Hospital Bahagia Ulu Kinta, Tanjung Rambutan 31250, Malaysia

7. Psychiatry Department, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia

8. Faculty of Business, Economics and Human Development, University Malaysia Terengganu, Kuala Terengganu 21030, Malaysia

9. Department of Psychological Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur 50603, Malaysia

10. Department of Educational Psychology & Counselling, Faculty of Education, Universiti Malaya, Kuala Lumpur 50603, Malaysia

11. School of Business, Asia Pacific University of Technology and Innovation, Kuala Lumpur 57000, Malaysia

12. Center for Community Health Studies (ReaCH), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia

13. Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia

Abstract

Medication adherence, especially among children and adolescents with psychiatric disorders, is often seen as a major treatment challenge. The purpose of this study is to systematically review studies addressing specific aspects of parental factors that are positively or negatively associated with medication adherence among children and adolescents with psychiatric disorders. A systematic literature search of English language publications, from inception through December 2021, was conducted from PubMed, Scopus, and MEDLINE databases. This review has complied with Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines. A total of 23 studies (77,188 participants) met inclusion criteria. Nonadherence rates ranged between 8% to 69%. Parents’ socioeconomic background, family living status and functioning, parents’ perception and attitude towards the importance of medication taking in treating psychiatric disorders, and parents’ mental health status are significant parental characteristics associated with medication adherence in children and adolescents with psychiatric disorders. In conclusion, by identifying specific parental characteristics related to the medication adherence of children and adolescents with psychiatric disorders, targeted interventions on parents could be developed to guide parents in improving their child’s medication adherence.

Funder

Fundamental Research Grant Scheme

Publisher

MDPI AG

Subject

Health Information Management,Health Informatics,Health Policy,Leadership and Management

Reference74 articles.

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2. How Is COVID-19 Pandemic Impacting Mental Health of Children and Adolescents?;Oliveira;Int. J. Disaster Risk Reduct.,2020

3. Meherali, S., Punjani, N., Louie-Poon, S., Abdul Rahim, K., Das, J.K., Salam, R.A., and Lassi, Z.S. (2021). Mental Health of Children and Adolescents Amidst COVID-19 and Past Pandemics: A Rapid Systematic Review. Int. J. Environ. Res. Public Health, 18.

4. Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19: A Meta-analysis;Racine;JAMA Pediatr.,2021

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