Post-Ischemic Stroke Cardiovascular Risk Prevention and Management

Author:

Guo Yilei1ORCID,Pan Danping1,Wan Haitong234,Yang Jiehong1

Affiliation:

1. College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China

2. The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310003, China

3. Institute of Cardio-Cerebrovascular Disease, Zhejiang Chinese Medical University, Hangzhou 310053, China

4. Key Laboratory of TCM Encephalopathy of Zhejiang Province, Hangzhou 310053, China

Abstract

Cardiac death is the second most common cause of death among patients with acute ischemic stroke (IS), following neurological death resulting directly from acute IS. Risk prediction models and screening tools including electrocardiograms can assess the risk of adverse cardiovascular events after IS. Prolonged heart rate monitoring and early anticoagulation therapy benefit patients with a higher risk of adverse events, especially stroke patients with atrial fibrillation. IS and cardiovascular diseases have similar risk factors which, if optimally managed, may reduce the incidence of recurrent stroke and other major cardiovascular adverse events. Comprehensive risk management emphasizes a healthy lifestyle and medication therapy, especially lipid-lowering, glucose-lowering, and blood pressure-lowering drugs. Although antiplatelet and anticoagulation therapy are preferred to prevent cardiovascular events after IS, a balance between preventing recurrent stroke and secondary bleeding should be maintained. Optimization of early rehabilitation care comprises continuous care across environments thus improving the prognosis of stroke survivors.

Funder

National Key R&D Program of China

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Key Laboratory of TCM Encephalopathy of Zhejiang Province

Publisher

MDPI AG

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