Abstract
Revisiting the classical model by Ross and Kermack-McKendrick, the Susceptible–Infectious–Recovered (SIR) model used to formalize the COVID-19 epidemic, requires improvements which will be the subject of this article. The heterogeneity in the age of the populations concerned leads to considering models in age groups with specific susceptibilities, which makes the prediction problem more difficult. Basically, there are three age groups of interest which are, respectively, 0–19 years, 20–64 years, and >64 years, but in this article, we only consider two (20–64 years and >64 years) age groups because the group 0–19 years is widely seen as being less infected by the virus since this age group had a low infection rate throughout the pandemic era of this study, especially the countries under consideration. In this article, we proposed a new mathematical age-dependent (Susceptible–Infectious–Goneanewsusceptible–Recovered (SIGR)) model for the COVID-19 outbreak and performed some mathematical analyses by showing the positivity, boundedness, stability, existence, and uniqueness of the solution. We performed numerical simulations of the model with parameters from Kuwait, France, and Cameroon. We discuss the role of these different parameters used in the model; namely, vaccination on the epidemic dynamics. We open a new perspective of improving an age-dependent model and its application to observed data and parameters.
Subject
Health Information Management,Health Informatics,Health Policy,Leadership and Management
Reference76 articles.
1. Ourworldindata on Fatalityhttps://ourworldindata.org/grapher/case-fatality-rate-of-covid-19-vs-median-age
2. Risk factors for mortality in hospitalized patients with COVID-19 at the start of the pandemic in Belgium: A retrospective cohort study;Van Halem;BMC Infect. Dis.,2020
3. Clinical course and factors associated with outcomes among 1904 patients hospitalized with COVID-19 in Germany: an observational study
4. National case fatality rates of the COVID-19 pandemic
5. Cohort profile: SARS-CoV-2/COVID-19 hospitalised patients in Switzerland
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献