Preliminary Results of Preoperative Planning Using 3D Printing and Augmented Reality in Cryotherapy Treatment of Giant Cell Tumor of Bone—CRIO2AR Project

Author:

D’Arienzo Antonio1,Scognamiglio Branimir1,Campo Francesco Rosario1,Cosseddu Fabio1ORCID,Ruinato Damiano Alfio1,Ipponi Edoardo1,Carbone Marina23ORCID,Condino Sara23ORCID,Ferrari Vincenzo23ORCID,Andreani Lorenzo1,Capanna Rodolfo1,Parchi Paolo Domenico1ORCID

Affiliation:

1. Department of Orthopedics and Trauma Surgery, University of Pisa, 56124 Pisa, Italy

2. Department of Information Engineering, University of Pisa, 56124 Pisa, Italy

3. EndoCAS Center, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56124 Pisa, Italy

Abstract

Giant Cell Tumor of Bone is a benign tumor with high local aggressive expansion, which, in rare cases, spreads metastasis. Surgical treatment, which often consists of wide curettage to reduce recurrence risk, can lower the quality of life for those affected. Along with aggressive surgery, adjuvant intraoperative techniques have been implemented such as PMMA and cryotherapy. One of the most widely used cryotherapy techniques involves the use of probes to generate ice balls, which have been scientifically shown to have various impacts on the tumor. Although this has been acknowledged, no one has yet tested a way to accurately plan the positioning of cryotherapy probes before surgery, according to the research conducted by the authors. CRIO2AR is a randomized clinical prospective ongoing study by which it will be experimented via preoperative planning of ice probes placement using AR and 3D printing technologies. By studying a single clinical case with these technologies, the surgeon gains better awareness of patient’s anatomy and tumor localization. Preliminary results are shown in the article. The first results are confirming that these technologies are applicable in clinical practice. Secondly, preoperative planning is proving to be reliable, easily replicable, and useful for the surgeon.

Funder

Italian Ministry of Education and Research

Publisher

MDPI AG

Subject

Health Information Management,Health Informatics,Health Policy,Leadership and Management

Reference17 articles.

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