Effects of a Raisin Supplement on Cognitive Performance, Quality of Life, and Functional Activities in Healthy Older Adults. Randomized Clinical Trial
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Published:2023-06-20
Issue:12
Volume:15
Page:2811
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ISSN:2072-6643
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Container-title:Nutrients
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language:en
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Short-container-title:Nutrients
Author:
Rodrigo-Gonzalo María José12, González-Manzano Susana123ORCID, Pablos-Hernández María Carmen4, Méndez-Sánchez Roberto23ORCID, Ayuda Duran Begoña1ORCID, González-Sánchez Jesús25ORCID, Barbero-Iglesias Fausto23, González-Paramás Ana María1ORCID, Recio-Rodríguez José Ignacio25ORCID
Affiliation:
1. Grupo de Investigación de Polifenoles (GIP-USAL), Universidad de Salamanca, E-37007 Salamanca, Spain 2. Facultad de Enfermería y Fisioterapia, Universidad de Salamanca, E-37007 Salamanca, Spain 3. Grupo de Fisioterapia, Recuperación Funcional y Ejercicio Terapéutico del Instituto de Investigación Biomédica de Salamanca (IBSAL), E-37007 Salamanca, Spain 4. Hospital Universitario de Salamanca, Universidad de Salamanca, E-37007 Salamanca, Spain 5. Unidad de Investigación en Atención Primaria de Salamanca (APISAL), Instituto de Investigación Biomédica de Salamanca (IBSAL), Red de Investigación en Cronicidad, Atención Primaria y Promoción de la Salud (RICAPPS), E-37007 Salamanca, Spain
Abstract
The objective of this study was to evaluate the effects of consuming 50 g of raisins on cognitive performance, quality of life, and functional activities in healthy older adults. This is a parallel randomized controlled clinical trial, in which 80 subjects over 70 years of age participated. For 6 months, the intervention group (IG; n = 40) consumed 50 g of raisins per day added to their usual diet, whereas the control group (CG; n = 40) received no supplement. All variables were measured at baseline and at 6 months. Cognitive performance assessed with the Montreal Cognitive Assessment (MOCA) test shows a difference of 3.27 points (95% CI 1.59 to 4.96), p ≤ 0.001, favorable to the IG, after the intervention. Among the cognitive performances, an improvement is observed in the IG in orientation, assessed both with the MOCA test 0.49 (95% CI 0.10 to 0.87), p = 0.014, and with the Mini-Mental State Examination (MMSE) test, 0.36 (95% CI 0.02 to 0.70), p = 0.038. In visuospatial/executive capacity and in language, improvements were also observed in the IG, 1.36 (95% CI 0.77 to 1.95), p = 0.001, and 0.54 points (95% CI 0.12 to 0.96), p = 0.014, respectively. Immediate and delayed recall, assessed with the Rey Auditory Verbal Learning Test, improved in the IG. In addition, the IG showed a better quality of life and greater autonomy in instrumental activities of daily living after 6 months. No significant changes were observed in the rest of the variables analyzed. Therefore, the consumption of 50 g of raisins produces a slight improvement in cognitive performance, quality of life, and functional activities in the elderly.
Funder
Regional Health Management of Castilla y León Ministry of Science and Innovation Junta de Castilla y León
Subject
Food Science,Nutrition and Dietetics
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