Affiliation:
1. Institute of Microbiology, Department of Molecular and Translational Medicine, University of Brescia-ASST Spedali Civili, 25123 Brescia, Italy
Abstract
Europe has faced a massive spread of the varicella-zoster virus through the years. Since the introduction of an effective vaccine, complications and severe forms of chickenpox have been restricted. Nevertheless, among the population, some categories need specific care, such as pregnant women, who present one of the most fragile conditions facing this infection, both for the mother and the fetus. In this review, we highlight how the varicella-zoster virus can be dangerous during pregnancy, underlining the problem of treatment and vaccination, and collect information about the European epidemiology among this particular category of women.
Subject
Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics
Reference66 articles.
1. Varicella-zoster virus;Arvin;Clin. Microbiol. Rev.,1996
2. Molecular mechanisms of varicella zoster virus pathogenesis;Zerboni;Nat. Rev. Microbiol.,2014
3. Varicella Zoster in pregnancy;Nanthakumar;Eur. J. Obstet. Gynecol. Reprod. Biol.,2021
4. Varicella-zoster virus infection: Natural history, clinical manifestations, immunity and current and future vaccination strategies;Freer;New Microbiol.,2018
5. Varicella -Zoster virus tranfer to skin by T cells and modulation of viral replication by epidermal cell interferon-alpha;Ku;J. Exp. Med.,2002