The Inflammatory Bowel Disease—Disk Tool for Assessing Disability in Inflammatory Bowel Disease Patients: Validation of the Greek Version

Author:

Katsoula Anastasia1ORCID,Axiaris Georgios2,Mpitouli Afroditi3,Palatianou Maria4,Christidou Angeliki5,Dimitriadis Nikolaos6,Nakos Andreas7,Pastras Ploutarchos8,Kourkoulis Panagiotis9,Karatzas Pantelis10,Moutzoukis Miltiadis11,Zlatinoudis Charalampos12,Philippidis Athanasios13,Kourikou Anastasia14,Kokkotis Georgios15,Gklavas Antonios16,Machaira Angeliki17,Mantaka Aikaterini18,Talimtzi Persefoni19ORCID,Anagnostopoulou Evaggelia18,Koutroubakis Ioannis E.17ORCID,Papaconstantinou Ioannis16,Bamias Georgios15,Manolakopoulos Spilios14,Mathou Nicoletta20,Paraskeva Konstantina20,Protopappas Andreas13,Tsironi Eftychia12,Katsanos Konstantinos H.11,Christodoulou Dimitrios K.11,Papatheodoridis Georgios10ORCID,Michalopoulos Georgios9,Theocharis Georgios8,Triantos Christos8ORCID,Pachiadakis Ioannis7,Soufleris Konstantinos6,Viazis Nikolaos5ORCID,Mantzaris Gerassimos J.5ORCID,Tribonias Georgios4,Tzouvala Maria4,Theodoropoulou Angeliki3,Karmiris Konstantinos3,Zampeli Evanthia2,Michopoulos Spyridon2ORCID,Haidich Anna-Bettina19ORCID,Giouleme Olga1

Affiliation:

1. Department of Gastroenterology and Hepatology, 2nd Propedeutic Department of Internal Medicine, Medical School, Aristotle University, 54124 Thessaloniki, Greece

2. Department of Gastroenterology, Alexandra General Hospital, 11528 Athens, Greece

3. Department of Gastroenterology, Venizeleio General Hospital, 71409 Heraklion, Greece

4. Department of Gastroenterology, General Hospital of Nikaia-Piraeus “Agios Panteleimon”, General Hospital Ditikis Attikis “Agia Varvara”, 12351 Athens, Greece

5. Department of Gastroenterology, GHA ‘Evaggelismos—Polykliniki’, 10676 Athens, Greece

6. Department of Gastroenterology, Theagenio Anticancer Hospital of Thessaloniki, 54639 Thessaloniki, Greece

7. Department of Gastroenterology and Hepatology, 424 Military General Hospital, 54124 Thessaloniki, Greece

8. GI-Unit, Department of Internal Medicine, University Hospital of Patras, 26504 Patras, Greece

9. Department of Gastroenterology, Tzaneion General Hospital, 18536 Piraeus, Greece

10. Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, General Hospital of Athens “Laiko”, 11527 Athina, Greece

11. Department of Gastroenterology, University Hospital of Ioannina Medical School, 45500 Ioannina, Greece

12. Department of Gastroenterology, Metaxa Memorial General Hospital, 18537 Piraeus, Greece

13. Gastroenterology and Hepatology Division of the First Propedeutic Department of Internal Medicine, AHEPA University Hospital, 54636 Thessaloniki, Greece

14. Gastroenterology-Liver Unit, Second Department of Internal Medicine, Hippokratio General Hospital, National and Kapodistrian University of Athens, 54643 Athens, Greece

15. GI-Unit, 3rd Academic Department of Internal Medicine, Sotiria Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece

16. Department of Surgery, Aretaieion University Hospital, 11528 Athens, Greece

17. Department of Gastroenterology, University Hospital of Heraklion, 71500 Heraklion, Greece

18. Department of Gastroenterology, General Hospital of Chania “Agios Georgios”, 73300 Chania, Greece

19. Laboratory of Hygiene, Social—Preventive Medicine and Medical Statistics, Faculty of Medicine, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece

20. Department of Gastroenterology, “Konstantopoulio-Patission” General Hospital, 14233 Nea Ionia, Greece

Abstract

Background: The Inflammatory Bowel Disease-Disk (IBD-Disk) is a physician-administered tool that evaluates the functional status of patients with Inflammatory Bowel Disease (IBD). The aim of our study was to validate the content of the IBD-Disk in a Greek cohort of IBD patients. Methods: Two questionnaires [the IBD Disk and the IBD-Disability Index (IBD-DI)] were translated into Greek and administered to IBD patients at baseline visit, after 4 weeks and 6 months. Validation of the IBD Disk included measuring of concurrent validity, reproducibility, and internal consistency. Results: A total of 300 patients were included at baseline and 269 at follow-up. There was a good correlation between the total scores of the IBD-Disk and IBD-DI at baseline (Pearson correlation 0.87, p < 0.001). Reproducibility of the total IBD-Disk score was very good [intra-class correlation coefficient (ICC), 95% confidence interval (CI) 0.89 (0.86–0.91)]. Cronbach’s coefficient alpha for all items achieved 0.90 (95%CI 0.88–0.92), demonstrating a very good homogeneity of the IBD-Disk items. Female gender and extraintestinal manifestations were significantly associated with a higher IBD-Disk total score. Conclusions: The Greek version of the IBD-Disk proved to be a reliable and valid tool in detecting and assessing IBD-related disability in a Greek cohort of IBD patients.

Funder

Hellenic Group for the Study of Inflammatory Bowel Disease

Publisher

MDPI AG

Subject

General Medicine

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