Cost-Effectiveness in Alternative Treatment Options for Pancreatic Pseudocysts

Author:

Boyanov Nikola12,Milinich Nikol2ORCID,Shtereva Katina2ORCID,Madzharova Katerina2,Tufkova Stoilka13,Penkova-Radicheva Mariana4,Radicheva Daniela4,Shopov Neno5

Affiliation:

1. Medical Simulation Training Center, Research Institute, Medical University of Plovdiv, 4000 Plovdiv, Bulgaria

2. Department of Gastroenterology, Pulmed University Hospital, 4000 Plovdiv, Bulgaria

3. Department of Clinical Toxicology, St. George University Hospital, 4000 Plovdiv, Bulgaria

4. Second Department of Internal Medicine Therapy, Medical Faculty, Trakia University, 6000 Stara Zagora, Bulgaria

5. Department of Surgery, Pulmed University Hospital, 4000 Plovdiv, Bulgaria

Abstract

Background and Objectives: Pancreatic pseudocysts often arise as complications of pancreatitis and present unique challenges in clinical management, encompassing considerations for both technical aspects and financial implications. Before the advancements of invasive gastroenterology, pancreatic pseudocysts have been drained surgically for many years. Nowadays, we have less invasive techniques with higher efficiency and lower mortality rates, however, they remain cost-challenging for most countries. Materials and Methods: We present four patients (two males and two females) with pancreatic pseudocysts who underwent endoscopic ultrasound-guided transgastric drainage using plastic stents accompanied by a standard lavage protocol using a nasocystic catheter. Results: All four patients had successful outcomes, and a follow-up at 6 months revealed no traces of the pseudocysts or any significant long-term complications. One acute complication (arterial bleeding) and one late complication (stent migration) were observed. As the study aimed to present a cheaper option for draining pancreatic pseudocysts, we investigated and compared costs for the materials we utilized and those associated with lumen-apposing metal stents. Upon compiling the data, a notable advantage was evident in favour of our method. Conclusions: While EUS-guided drainage of pancreatic pseudocysts using lumen-apposing metal stents (LAMSs) represents a high-end strategy for treating pancreatic pseudocysts, our method demonstrates better cost-effectiveness without compromising efficacy.

Publisher

MDPI AG

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