Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review-Reference-Cited by-同舟云学术

Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review

Published:2023-10-20 Issue:5 Volume:11 Page:168
ISSN:2226-4787
Container-title:Pharmacy
language:en
Short-container-title:Pharmacy

Author:

Sharma Rishabh¹^ORCID,Mahajan Neil²,Fadaleh Sarah Abu¹,Patel Hawa¹,Ivo Jessica¹,Faisal Sadaf¹^ORCID,Chang Feng¹^ORCID,Lee Linda³⁴⁵,Patel Tejal¹³⁴^ORCID

Affiliation:

1. School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, Canada

2. Faculty of Health, Western University, 1151 Richmond St, London, ON N6A 5B9, Canada

3. CFFM MINT Memory Clinic, 25 Joseph St, Kitchener, ON N2G 4X6, Canada

4. Schlegel-UW Research Institute for Aging, 250 Laurelwood Dr, Waterloo, ON N2J 0E2, Canada

5. Department of Family Medicine, McMaster University, 100 Main St W 5th Floor, Hamilton, ON L8P 1H6, Canada

Abstract

Persons diagnosed with dementia are often faced with challenges related to polypharmacy and inappropriate medication use and could benefit from regular medication reviews. However, the benefit of such reviews has not been examined in this population. Therefore, the current scoping review was designed to identify the gaps in the current knowledge regarding the impact of medication reviews on the clinical outcomes in older adults with dementia. Relevant studies were identified by searching three databases (Ovid MEDLINE, Ovid EMBASE, and Scopus) from inception to January 2022 with a combination of keywords and medical subject headings. After the removal of duplicates and ineligible articles, 22 publications of the initial 8346 were included in this review. A total of 57 outcomes were identified, including those pertaining to the evaluation of medication use (n = 17), drug-related interventions (n = 11), drug-related problems (n = 10), dementia-related behavioral symptoms (n = 8), cost-effectiveness (n = 2), drug-related hospital admissions (n = 1), as well as outcomes classified as other (n = 7). Gaps identified through this scoping review included the paucity of studies measuring the impact of medication reviews on the medication management capacity and medication adherence, quality of life, and mortality.

Publisher

MDPI AG

Subject

Microbiology (medical),Immunology,Immunology and Allergy

Link

https://www.mdpi.com/2226-4787/11/5/168/pdf

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