Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics-Reference-Cited by-同舟云学术

Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics

Published:2023-06-15 Issue:3 Volume:11 Page:101
ISSN:2226-4787
Container-title:Pharmacy
language:en
Short-container-title:Pharmacy

Author:

Stratton Timothy P.¹,Olson Anthony W.²^ORCID

Affiliation:

1. University of Minnesota College of Pharmacy, Department of Pharmacy Practice and Pharmaceutical Sciences, Duluth, MN 55812, USA

2. Essentia Institute of Rural Health, Duluth, MN 55805, USA

Abstract

Truly personalized precision medicine combines pharmacogenomics (PGx), a person’s lived medication experiences and ethics; person-centeredness lies at the confluence of these considerations. A person-centered perspective can help inform PGx-related treatment guidelines, shared decision-making for PGx-related therapeutics and PGx-related healthcare policy. This article examines the interplay between these components of person-centered PGx-related care. Ethics concepts addressed include privacy, confidentiality, autonomy, informed consent, fiduciary responsibility, respect, the burden of pharmacogenomics knowledge for both the patient and healthcare provider and the pharmacist’s ethical role in PGx-testing. Incorporating the patient’s lived medication experience and ethics principles into PGx-based discussions of treatment can optimize the ethical, person-centered application of PGx testing to patient care.

Publisher

MDPI AG

Subject

Microbiology (medical),Immunology,Immunology and Allergy

Link

https://www.mdpi.com/2226-4787/11/3/101/pdf

Reference56 articles.

1. National Cancer Institute (2023, April 17). Precision Medicine, Available online: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/precision-medicine.

2. Person-centered care from a relational ethics perspective for the delivery of high quality and safe healthcare: A scoping review;Tomaselli;Front. Public Health,2020

3. Cipolle, R.J., Strand, L.M., and Morley, P.C. (2012). Pharmaceutical Care Practice: The Patient Centered Approach to Medication Management, McGraw-Hill. [3rd ed.].

4. Institute of Medicine (2001). Crossing the Quality Chasm: A New Health System for the 21st Century, National Academy Press.

5. What is the right thing to do: Use of a relational ethic framework to guide clinical decision-making;Pollard;Int. J. Caring Sci.,2015

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A comprehensive Thai pharmacogenomics database (TPGxD‐1): Phenotype prediction and variants identification in 942 whole‐genome sequencing data;Clinical and Translational Science;2024-06

2. Patient-centered precision care in anaesthesia – the PC-square (PC)2 approach;Current Opinion in Anaesthesiology;2024-01-22

3. Pharmacogenomics to support mental health medication therapy management: Clinical practice considerations and a conceptual framework to enhance patient care;JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY;2023-12-03