The Impact of Cardiovascular Antecedents on the Prognosis of COVID-19 Critically Ill Patients

Author:

Nechita Luiza Camelia1,Ignat Mariana Daniela1,Balta Alexia Anastasia Stefania1,Barbu Raisa Eloise1,Baroiu Liliana23ORCID,Voinescu Doina Carina24,Nechita Aurel25,Debita Mihaela36,Busila Camelia25,Stefanopol Ioana Anca57ORCID

Affiliation:

1. Doctoral School of Biomedical Sciences, ‘Dunarea de Jos’ University, 800008 Galati, Romania

2. Clinical Medical Department, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos’ University, 800008 Galati, Romania

3. ‘Sf. Cuv. Parascheva’ Clinical Hospital of Infectious Diseases, 800179 Galati, Romania

4. ‘Sf. Apostol Andrei’ Clinical Emergency County Hospital, 800578 Galati, Romania

5. ‘Sf. Ioan’ Clinical Hospital for Children, 800487 Galati, Romania

6. Medical Department, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos’ University, 800008 Galati, Romania

7. Clinical Surgical Department, Faculty of Medicine and Pharmacy, ‘Dunarea de Jos’ University, 800008 Galati, Romania

Abstract

Background/Objectives: The objective of the study is to analyze the impact of cardiovascular history on mortality in COVID-19 patients, hospitalized in the intensive care unit with indications for continuous positive airway pressure (CPAP) and subsequently mechanical ventilation, without oncological disease. Methods: A retrospective observational study was carried out on a group of 108 critical COVID-19 patients. We compared demographic data, paraclinical and clinical parameters, days of hospitalization, and mortality rate between two groups of patients, one group with a history of cardiovascular disease (81 patients) and a group without a history of cardiovascular disease (27 patients). Results: Patients with cardiovascular antecedents had a higher mortality rate than those without cardiovascular antecedents, presenting severe forms with shorter survival time in the intensive care unit and increased inflammatory evidence. Compared to patients without a history of cardiovascular illness, those with cardiovascular disease had a lower average age, and developed a severe form of COVID-19. Conclusions: Cardiovascular antecedents can worsen the prognosis of patients with COVID-19, requiring a careful screening and multidisciplinary approach.

Publisher

MDPI AG

Reference61 articles.

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