Can BPA Analogs Affect Cellular and Biochemical Responses in the Microalga Phaeodactylum tricornutum Bohlin?

Author:

Fabrello Jacopo1,Ciscato Maria1,Moschin Emanuela1,Vecchia Francesca Dalla1,Moro Isabella1ORCID,Matozzo Valerio1ORCID

Affiliation:

1. Department of Biology, University of Padova, Via Basssi 58/B, 35131 Padova, Italy

Abstract

Bisphenol A analogs (BPA analogs) are emerging contaminants with a rising production caused by the replacement of BPA with these compounds. The increased production of BPA analogs is leading to their increased release into various ecosystems, including marine ones. The aim of this study was to evaluate the biological effects of BPA analogs on a primary producer, the diatom Phaeodactylum tricornutum Bohlin. Three different BPA analogs (BPAF, BPF, and BPS) and their mixture were tested at the environmental relevant concentration of 300 ng/L. Growth, cell size and several biomarkers of oxidative stress and oxidative damage were measured. Our results indicated that the tested compounds caused a reduced growth rate and induced oxidative stress, altering many antioxidant enzymes in P. tricornutum. However, no oxidative damages were observed.

Publisher

MDPI AG

Subject

Pollution,Pharmacology,Toxicology

Reference57 articles.

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