The Future of Origin of Life Research: Bridging Decades-Old Divisions

Author:

Preiner MartinaORCID,Asche SilkeORCID,Becker SidneyORCID,Betts Holly C.,Boniface Adrien,Camprubi EloiORCID,Chandru Kuhan,Erastova ValentinaORCID,Garg Sriram G.,Khawaja Nozair,Kostyrka Gladys,Machné RainerORCID,Moggioli Giacomo,Muchowska Kamila B.ORCID,Neukirchen SinjeORCID,Peter Benedikt,Pichlhöfer Edith,Radványi Ádám,Rossetto DanieleORCID,Salditt Annalena,Schmelling Nicolas M.ORCID,Sousa Filipa L.,Tria Fernando D. K.,Vörös Dániel,Xavier Joana C.ORCID

Abstract

Research on the origin of life is highly heterogeneous. After a peculiar historical development, it still includes strongly opposed views which potentially hinder progress. In the 1st Interdisciplinary Origin of Life Meeting, early-career researchers gathered to explore the commonalities between theories and approaches, critical divergence points, and expectations for the future. We find that even though classical approaches and theories—e.g., bottom-up and top-down, RNA world vs. metabolism-first—have been prevalent in origin of life research, they are ceasing to be mutually exclusive and they can and should feed integrating approaches. Here we focus on pressing questions and recent developments that bridge the classical disciplines and approaches, and highlight expectations for future endeavours in origin of life research.

Funder

Deutsche Forschungsgemeinschaft

European Research Council

Volkswagen Foundation

Vienna Science and Technology Fund

National Research, Development and Innovation Office

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

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