Molecular Diagnostics of Cryptococcus spp. and Immunomics of Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome-Reference-Cited by-同舟云学术

Molecular Diagnostics of Cryptococcus spp. and Immunomics of Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome

Published:2024-05-13 Issue:5 Volume:12 Page:101
ISSN:2079-9721
Container-title:Diseases
language:en
Short-container-title:Diseases

Author:

Vlasova-St. Louis Irina¹^ORCID,Mohei Hesham²^ORCID

Affiliation:

1. GenoHealth LLC, El Paso, TX 79912, USA

2. Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

Abstract

Cryptococcal infection poses a significant global public health challenge, particularly in regions near the equator. In this review, we offer a succinct exploration of the Cryptococcus spp. genome and various molecular typing methods to assess the burden and genetic diversity of cryptococcal pathogens in the environment and clinical isolates. We delve into a detailed discussion on the molecular pathogenesis and diagnosis of immune reconstitution inflammatory syndrome (IRIS) associated with cryptococcosis, with a specific emphasis on cryptococcal meningitis IRIS (CM-IRIS). Our examination includes the recent literature on CM-IRIS, covering host cellulomics, proteomics, transcriptomics, and genomics.

Publisher

MDPI AG

Link

https://www.mdpi.com/2079-9721/12/5/101/pdf

Reference106 articles.

1. Vlasova-St. Louis, I., Gorzalski, A., and Pandori, M. (2021). Applications of RNA-Seq in Biology and Medicine, IntechOpen.

2. Rapid Lineage Assignment of Severe Acute Respiratory Syndrome Coronavirus 2 Cases through Automated Library Preparation, Sequencing, and Bioinformatic Analysis;Gorzalski;J. Mol. Diagn.,2023

3. Smith, D.J., Gold, J.A.W., Benedict, K., Wu, K., Lyman, M., Jordan, A., Medina, N., Lockhart, S.R., Sexton, D.J., and Chow, N.A. (2023). Public Health Research Priorities for Fungal Diseases: A Multidisciplinary Approach to Save Lives. J. Fungi, 9.

4. Fang, W., Wu, J., Cheng, M., Zhu, X., Du, M., Chen, C., Liao, W., Zhi, K., and Pan, W. (2023). Diagnosis of invasive fungal infections: Challenges and recent developments. J. Biomed. Sci., 30.

5. Adaptive immunology of Cryptococcus neoformans infections—An update;Chen;Front. Immunol.,2023