Trends in Nanoparticles for Leishmania Treatment: A Bibliometric and Network Analysis

Author:

Mazón-Ortiz Gabriel12ORCID,Cerda-Mejía Galo12,Gutiérrez Morales Eberto1,Diéguez-Santana Karel13ORCID,Ruso Juan M.2ORCID,González-Díaz Humberto456ORCID

Affiliation:

1. Facultad Ciencias de la Vida, Facultad Ciencias de la Tierra y Agua, Universidad Regional Amazónica Ikiam, Parroquia Muyuna km 7 vía Alto Tena, Tena 150150, Napo, Ecuador

2. Soft Matter and Molecular Biophysics Group, Department of Applied Physics and Institute of Materials (iMATUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

3. Wood Engineering Department, University of Bio-Bio, Concepcion 4030000, Chile

4. Department of Organic and Inorganic Chemistry, University of the Basque Country UPV/EHU, 48940 Leioa, Spain

5. Basque Center for Biophysics CSIC-UPVEH, University of Basque Country UPV/EHU, 48940 Leioa, Spain

6. IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain

Abstract

Leishmaniasis is a neglected tropical illness with a wide variety of clinical signs ranging from visceral to cutaneous symptoms, resulting in millions of new cases and thousands of fatalities reported annually. This article provides a bibliometric analysis of the main authors’ contributions, institutions, and nations in terms of productivity, citations, and bibliographic linkages to the application of nanoparticles (NPs) for the treatment of leishmania. The study is based on a sample of 524 Scopus documents from 1991 to 2022. Utilising the Bibliometrix R-Tool version 4.0 and VOSviewer software, version 1.6.17 the analysis was developed. We identified crucial subjects associated with the application of NPs in the field of antileishmanial development (NPs and drug formulation for leishmaniasis treatment, animal models, and experiments). We selected research topics that were out of date and oversaturated. Simultaneously, we proposed developing subjects based on multiple analyses of the corpus of published scientific literature (title, abstract, and keywords). Finally, the technique used contributed to the development of a broader and more specific “big picture” of nanomedicine research in antileishmanial studies for future projects.

Publisher

MDPI AG

Subject

General Medicine

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