Catalytic Hydrolysis of Tricresyl Phosphate by Ruthenium (III) Hydroxide and Iron (III) Hydroxide towards Sensing Application

Abstract

Tricresyl phosphate (TCP) is an organophosphorous neurotoxin that has been detected in water, soil and air. Exposure to TCP in cockpit and cabin air poses a severe threat to flight safety and the health of the aircraft cabin occupants. Conventional methods for the detection of TCP in various samples are gas or liquid chromatography coupled to mass spectrometry, which are complex and expensive. To develop a simple low-cost methodology for the real-time monitoring of TCP in the environment, an effective catalyst is demanded for the hydrolysis of TCP under neutral condition. In this study, Ruthenium (III) hydroxide and Iron (III) hydroxide are found to facilitate the production of the alcoholysis and hydrolysis products of TCP, suggesting their role as a catalyst. With this finding, these metal hydroxides provide new potential to realize not only simple colorimetric or electrochemical detection of TCP, but also a simple detoxication strategy for TCP in environment. In addition, the catalytic capability of Ru (III) or Fe (III) hydroxide for TCP gives a hint that they can potentially serve as catalysts for the hydrolysis of alcolyolysis of many other organophosphate compounds.