Preoperative Assessment and Management of Cardiovascular Risk in Patients Undergoing Non-Cardiac Surgery: Implementing a Systematic Stepwise Approach during the COVID-19 Pandemic Era

Author:

Bossone EduardoORCID,Cademartiri Filippo,AlSergani Hani,Chianese Salvatore,Mehta Rahul,Capone ValentinaORCID,Ruotolo Carlo,Tarrar Imran Hayat,Frangiosa Antonio,Vriz Olga,Maffei Vincenzo,Annunziata RobertoORCID,Galzerano Domenico,Ranieri BrigidaORCID,Sepe Chiara,Salzano AndreaORCID,Cocchia Rosangela,Majolo Massimo,Russo Giuseppe,Longo Giuseppe,Muto Mario,Fedelini Paolo,Esposito Ciro,Perrella AlessandroORCID,Guggino Gianluca,Raiola Eliana,Catalano Mara,De Palma Maurizio,Romano Luigia,Romano Gaetano,Coppola Ciro,Mauro Ciro,Mehta Rajendra H.

Abstract

Major adverse cardiac events, defined as death or myocardial infarction, are common causes of perioperative mortality and major morbidity in patients undergoing non-cardiac surgery. Reduction of perioperative cardiovascular risk in relation to non-cardiac surgery requires a stepwise patient evaluation that integrates clinical risk factors, functional status and the estimated stress of the planned surgical procedure. Major guidelines on preoperative cardiovascular risk assessment recommend to establish, firstly, the risk of surgery per se (low, moderate, high) and the related timing (elective vs. urgent/emergent), evaluate the presence of unstable cardiac conditions or a recent coronary revascularization (percutaneous coronary intervention or coronary artery bypass grafting), assess the functional capacity of the patient (usually expressed in metabolic equivalents), determine the value of non-invasive and/or invasive cardiovascular testing and then combine these data in estimating perioperative risk for major cardiac adverse events using validated scores (Revised Cardiac Risk Index (RCRI) or National Surgical Quality Improvement Program (NSQIP)). This stepwise approach has the potential to guide clinicians in determining which patients could benefit from cardiovascular therapy and/or coronary artery revascularization before non-cardiac surgery towards decreasing the incidence of perioperative morbidity and mortality. Finally, it should be highlighted that there is a need to implement specific strategies in the 2019 Coronavirus disease (COVID-19) pandemic to minimize the risk of transmission of COVID-19 infection during the preoperative risk assessment process.

Publisher

MDPI AG

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

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