1. Pediatric Endocrinology Unit, Department of Pediatrics, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba 80060-240, PR, Brazil
2. Department of Internal Medicine, Endocrine Division (SEMPR), Hospital de Clínicas, Universidade Federal do Paraná, Curitiba 80030-110, PR, Brazil
3. Department of Pediatrics, Universidade Federal do Paraná, Curitiba 80030-110, PR, Brazil